B7-H4 Antibody [Biotin]

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-28513B

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Product Datasheet / COA / SDS

Recombinant Monoclonal Antibody

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP3-28513AF350

Alexa Fluor 405

NBP3-28513AF405

Alexa Fluor 488

NBP3-28513AF488

Alexa Fluor 532

NBP3-28513AF532

Alexa Fluor 594

NBP3-28513AF594

Alexa Fluor 647

NBP3-28513AF647

Alexa Fluor 700

NBP3-28513AF700

Alexa Fluor 750

NBP3-28513AF750

Allophycocyanin

NBP3-28513APC

CoraFluor 1

NBP3-28513CL1

DyLight 350

NBP3-28513UV

DyLight 405

NBP3-28513V

DyLight 488

NBP3-28513G

DyLight 550

NBP3-28513R

DyLight 594

NBP3-28513DL594

DyLight 650

NBP3-28513C

DyLight 680

NBP3-28513FR

DyLight 755

NBP3-28513IR

FITC

NBP3-28513F

HRP

NBP3-28513H

Janelia Fluor 525

NBP3-28513JF525

Janelia Fluor 549

NBP3-28513JF549

Janelia Fluor 646

NBP3-28513JF646

Janelia Fluor 669

NBP3-28513JF669

mFluor Violet 450 SE

NBP3-28513MFV450

mFluor Violet 500 SE

NBP3-28513MFV500

mFluor Violet 610 SE

NBP3-28513MFV610

PE

NBP3-28513PE

PerCP

NBP3-28513PCP

Forumulation

Catalog #

Low Endotoxin, Azide and BSA Free

NBP3-28513

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Human

Applications

ELISA, Flow Cytometry, Functional

Label

Biotin

Antibody Source

Recombinant Monoclonal Human IgG₁ expressed in CHO

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all B7-H4 Antibodies »

Product Specifications

Immunogen

B7-H4 / VTCN1

Clonality

Monoclonal

Host

Human

Isotype

IgG₁

Description

The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Patent #: US20130058864

Applications for B7-H4 Antibody [Biotin]

Application

Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Functional

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: B7-H4

B7H4 is a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity. Although B7H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production. B7H4 deficient mice are only minimally affected, thus suggesting B7H4 is important in the fine tuning of the T-cell mediated immune response. B7H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7H4 could be a useful prognostic marker in Renal Cell Carcinoma (RCC). There are three different isoforms.

Long Name

B7 Homolog 4

Alternate Names

B7H4, B7S1, B7x, Vtcn1

Gene Symbol

VTCN1

Additional B7-H4 Products

Product Documents for B7-H4 Antibody [Biotin]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for B7-H4 Antibody [Biotin]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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