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DNA, RNA and Protein Synthesis Inhibitors: Small Molecules and Peptides

37 results for "DNA, RNA and Protein Synthesis Inhibitors Small Molecules and Peptides" in Products

37 results for "DNA, RNA and Protein Synthesis Inhibitors Small Molecules and Peptides" in Products

DNA, RNA and Protein Synthesis Inhibitors: Small Molecules and Peptides

Protein synthesis inhibitor

Chemical Name: 3'-[α-Amino-p-methoxyhydrocinnamamido]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
Purity: ≥98% (HPLC)
Protein synthesis inhibitor

Inhibitor of protein synthesis

Chemical Name: 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
Purity: ≥97% (HPLC)
Inhibitor of protein synthesis

DNA cross-linking antitumor agent

Alternate Names: Ametycine
Chemical Name: [1aS-(1aα,8β,8aα,8bα)]-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-methoxy-5-methylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione
Purity: ≥98% (HPLC)
DNA cross-linking antitumor agent

DNA synthesis inhibitor

Chemical Name: (+)-2'-Deoxy-2',2'-difluorocytidine hydrochloride
Purity: ≥98% (HPLC)
DNA synthesis inhibitor

Potent protein synthesis inhibitor

Alternate Names: Dehydrodidemnin B,DDB
Purity: ≥98% (HPLC)
Potent protein synthesis inhibitor

Nucleoside analog; inhibits DNA replication

Alternate Names: Cytosine b-D-arabinofuranoside
Chemical Name: 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone
Purity: ≥98% (HPLC)
Nucleoside analog; inhibits DNA replication

RNA synthesis inhibitor

Chemical Name: 3'-Deoxyadenosine
Purity: ≥98% (HPLC)
RNA synthesis inhibitor

Inhibitor of protein synthesis; antileukemic agent

Chemical Name: Cephalotaxine 4-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate
Purity: ≥98% (HPLC)
Inhibitor of protein synthesis; antileukemic agent

Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria

Alternate Names: LY 146032
Chemical Name: N-(1-Oxodecyl)-L-tryptophyl-D-asparaginyl-L-α-aspartyl-L-threonylglycyl-L-ornithinyl-L-α-aspartyl-D-alanyl-L-α-aspartylglycyl-D-seryl-(3R)-3-methyl-L-α-glutamyl-α,2-diamino-γ-oxo-benzene butanoic acid (13-4) lactone
Purity: ≥95% (HPLC)
Antibiotic; inhibits protein, DNA and RNA synthesis in gram-positive bacteria

Inhibits RNA polymerase

Chemical Name: 2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Purity: ≥95% (HPLC)
Inhibits RNA polymerase

Inhibitor of DNA and RNA polymerase

Chemical Name: (1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose
Purity: ≥95% (HPLC)
Inhibitor of DNA and RNA polymerase

Thymidylate synthetase inhibitor

Alternate Names: 5-FU
Chemical Name: 5-Fluoro-2,4-(1H,3H)-pyrimidinedione
Purity: ≥98% (HPLC)
Thymidylate synthetase inhibitor

JNK, SAPK and p38 activator

Chemical Name: (2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate
Purity: ≥98% (HPLC)
JNK, SAPK and p38 activator

Antibiotic; inhibits bacterial DNA synthesis

Alternate Names: CP 99219
Chemical Name: 7-[(1α,5α,6α)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesylate
Purity: ≥98% (HPLC)
Antibiotic; inhibits bacterial DNA synthesis

Antibiotic; inhibits bacterial DNA synthesis

Chemical Name: (S)-3,6-Diamino-N-((3S,9S,12S,15S,Z)3((2R,4S)-6-amino-4-hydroxy-1,2,3,4-tetrahydropyridin-2-yl)-9,12-bis(hydroxymethyl)-2,5,8,11,14-pentaoxo-6-(ureidomethylene)-1,4,7,10,13-pentaazacyclohexadecan-15-yl)hexanamide disulfate
Antibiotic; inhibits bacterial DNA synthesis

Purine analog; inhibits DNA synthesis

Chemical Name: 9-β-D-Arabinofuranosyl-2-fluoro-9H-purin-6-amine
Purity: ≥98% (HPLC)
Purine analog; inhibits DNA synthesis

DNA cross-linking antitumor agent

Alternate Names: Eloxatin
Chemical Name: Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II)
Purity: ≥98% (HPLC)
DNA cross-linking antitumor agent

DNA cross-linking antitumor agent

Alternate Names: NSC 241240,Paraplatin,JM 8
Chemical Name: cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II)
Purity: ≥98% (HPLC)
DNA cross-linking antitumor agent

DNA topoisomerase II inhibitor

Alternate Names: Daunomycin
Chemical Name: (8S,10S)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyransoyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione hydrochloride
Purity: ≥98% (HPLC)
DNA topoisomerase II inhibitor

Inhibitor of RNA helicase A (RHA)

Chemical Name: 4,7-Dichloro-1,3-dihydro-3-hydroxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-2H-indol-2-one
Purity: ≥98% (HPLC)
Inhibitor of RNA helicase A (RHA)

DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis

Alternate Names: NSC125066
Purity: ≥90% (HPLC)
DNA synthesis inhibitor. Induces pulmonary inflammation and fibrosis

DNA polymerase α, δ and ε inhibitor

Chemical Name: (3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol
Purity: ≥98% (HPLC)
DNA polymerase α, δ and ε inhibitor

Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Chemical Name: (3bS,4aS,5aS,6R,6aR,7aS,7bS,8aS,8bS)-3b,4,4a,6,6a,7a,7b,8b,9,10-Decahydro-6-hydroxy-8b-methyl-6a-(1-methylethyl)trisoxireno[4b,5:6,7:8a,9]phenanthro[1,2-c]furan-1(3H)-one
Purity: ≥98% (HPLC)
Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

RNA polymerase I inhibitor; also p53 pathway activator

Chemical Name: N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Purity: ≥98% (HPLC)
RNA polymerase I inhibitor; also p53 pathway activator

Purine nuceloside analog; inhibits DNA synthesis

Alternate Names: GW 506U78
Chemical Name: 9-β-D-Arabinofuranosyl-6-methoxy-9H-purin-2-amine
Purity: ≥98% (HPLC)
Purine nuceloside analog; inhibits DNA synthesis
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