Dopamine D2 R/DRD2: Small Molecules and Peptides
DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.
22 results for "Dopamine D2 R/DRD2 Small Molecules and Peptides" in Products
22 results for "Dopamine D2 R/DRD2 Small Molecules and Peptides" in Products
Dopamine D2 R/DRD2: Small Molecules and Peptides
DRD2 encodes the D2 subtype of the dopamine receptor that inhibits adenylyl cyclase activity. Alternative splicing of this G protein-coupled receptor results in two transcript variants encoding different isoforms. DRD2 plays a major role in the neural circuitry that mediates behavioral control, an ability that is essential for adaptive responding and is compromised in a variety of common neuropsychiatric disorders.
Caged dopamine; photolysed by UV light
| Purity: | ≥98% (HPLC) |
Selective D2-like agonist
| Chemical Name: | (4aR-trans)-4,4a,5,6,7,8,8a,9-Octahydro-5-propyl-1H-pyrazolo[3,4-g]quinoline hydrochloride |
| Purity: | ≥98% (HPLC) |
Dopamine precursor
| Alternate Names: | Levodopa |
| Chemical Name: | L-3,4-Dihydroxyphenylalanine |
| Purity: | ≥98% (HPLC) |
Dopamine antagonist; displays some D2 selectivity
| Chemical Name: | 4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity D3 agonist (D3 ≥ D2 > D4)
| Chemical Name: | (4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
Potent and selective D2 and D3 antagonist
| Chemical Name: | 3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
Standard selective D2-like antagonist
| Chemical Name: | (S)-(-)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
| Chemical Name: | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
| Purity: | ≥99% (HPLC) |
D2 and D3 antagonist (D3 > D2)
| Alternate Names: | (-)-Eticlopride |
| Chemical Name: | 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride |
| Purity: | ≥98% (HPLC) |
D2-like agonist (D2>D3>D4)
| Chemical Name: | N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)ergoline-8-carboxamide |
| Purity: | ≥99% (HPLC) |
D2-like agonist (D2>D3>D4)
| Chemical Name: | (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
Standard selective D2-like antagonist
| Chemical Name: | (RS)-(±)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
High affinity D2 antagonist
| Chemical Name: | 3-[[4-(4-Chlorophenyl)-4-hydroxypiperidin-l-yl]methyl-1H-indole |
| Purity: | ≥98% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
| Chemical Name: | 2-Methyl-4-(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine |
| Purity: | ≥98% (HPLC) |
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | ICI 204,636 |
| Chemical Name: | 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
| Purity: | ≥98% (HPLC) |
D2 and D3 agonist
| Alternate Names: | N 0923 |
| Chemical Name: | (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride |
| Purity: | ≥99% (HPLC) |
Selective D2-like agonist
| Chemical Name: | 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Highly potent D2-like antagonist; also 5-HT1A agonist
| Alternate Names: | YM 09151,YM 09151-2 |
| Chemical Name: | cis-5-Chloro-2-methoxy-4-(methylamino)-N-[2-methyl-1-(phenylmethyl)-3-pyrrolidinyl]benzamide |
| Purity: | ≥98% (HPLC) |
Dopamine receptor antagonist; antipsychotic
| Chemical Name: | 10-[2-(1-Methyl-2-piperidinyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective D2 agonist
| Chemical Name: | (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one (2Z)-2-butenedioate |
| Purity: | ≥98% (HPLC) |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% (HPLC) |
