CNV Dopamine

Name: CNV Dopamine
Brand: Tocris Bioscience
SKU: 6354

Tocris Bioscience, part of Bio-Techne | Catalog # 6354

COA / SDS

Caged dopamine; photolysed by UV light

Key Product Details

Description:	Caged dopamine; photolysed by UV light
Purity:	≥98% (HPLC)
Molecular Weight:	392.36

View Full Technical Details for CNV Dopamine

Technical Data
Citations

Biological Activity for CNV Dopamine

CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine (Cat. No. 3548); releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D₂ receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.

Technical Data for CNV Dopamine

M. Wt	392.36
Formula	C₁₈H₂₀N₂O₈
Storage	Store at -20°C
Purity	≥98% (HPLC)
InChi Key	TZSFDUOAUWDBIB-UHFFFAOYSA-N
Smiles	OC1=CC(CCN)=CC=C1OC(C(O)=O)C2=CC(OC)=C(OC)C=C2[N+]([O-])=O.NCCC3=CC=C(O)C(OC(C(O)=O)C4=CC(OC)=C(OC)C=C4[N+]([O-])=O)=C3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for CNV Dopamine

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	DMSO	39.24	100
	water	19.62	50

Preparing Stock Solutions for CNV Dopamine

The following data is based on the product molecular weight 392.36.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.55 mL	12.74 mL	25.49 mL
5 mM	0.51 mL	2.55 mL	5.10 mL
10 mM	0.25 mL	1.27 mL	2.55 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

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References for CNV Dopamine

References are publications that support the biological activity of the product.

Robinson Desensitized D₂ autoreceptors are resistant to trafficking. Sci.Rep. 2017 PMID: 28663556