Ropinirole

Name: Ropinirole
Brand: Tocris Bioscience
SKU: 3680

Tocris Bioscience, part of Bio-Techne | Catalog # 3680

Citations (13)

COA / SDS

Selective D2-like agonist

Key Product Details

Description:	Selective D₂-like agonist
Chemical Name:	4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride
Purity:	≥98% (HPLC)
Molecular Weight:	296.84

View Full Technical Details for Ropinirole

Technical Data
Citations

Biological Activity for Ropinirole

Ropinirole is a selective D₂-like receptor agonist (D₃ > D₂ > D₄). Causes biphasic spontaneous locomotor activity and contralateral circling in 6-OHDA-lesioned mice. Displays anti-Parkinsonian activity.

Technical Data for Ropinirole

M. Wt	296.84
Formula	C₁₆H₂₄N₂O.HCl
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	91374-20-8
PubChem ID	68727
InChi Key	XDXHAEQXIBQUEZ-UHFFFAOYSA-N
Smiles	O=C2NC1=CC=CC(CCN(CCC)CCC)=C1C2.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

Solubility for Ropinirole

	Solvent	Max Conc. mg/mL	Max Conc. mM
Solubility
	water	29.68	100
	DMSO	14.84	50

Preparing Stock Solutions for Ropinirole

The following data is based on the product molecular weight 296.84.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	3.37 mL	16.84 mL	33.69 mL
5 mM	0.67 mL	3.37 mL	6.74 mL
10 mM	0.34 mL	1.68 mL	3.37 mL
50 mM	0.07 mL	0.34 mL	0.67 mL

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References for Ropinirole

References are publications that support the biological activity of the product.

Tulloch Pharmacologic profile of ropinirole: a nonergoline DA agonist. Neurology 1997 PMID: 9222275
Eden Preclinical pharmacology of ropin. (SK&F 101468-A) a novel DA D₂ agonist. Pharmacol.Biochem.Behav. 1991 PMID: 1673248