Ropinirole
Tocris Bioscience, part of Bio-Techne | Catalog # 3680
Selective D2-like agonist
Key Product Details
Description
Selective D2-like agonist
Product Description
Ropinirole is a selective D2-like receptor agonist (D3 > D2 > D4). Causes biphasic spontaneous locomotor activity and contralateral circling in 6-OHDA-lesioned mice. Displays anti-Parkinsonian activity.Product Specifications
Molecular Weight
296.84
Formula
C16H24N2O.HCl
Storage
Desiccate at RT
Purity
≥98% (HPLC)
Chemical Name
4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride
CAS Number
91374-20-8
PubChem ID
68727
InChI Key
XDXHAEQXIBQUEZ-UHFFFAOYSA-N
SMILES
O=C2NC1=CC=CC(CCN(CCC)CCC)=C1C2.Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 29.68 | 100 | |
| DMSO | 14.84 | 50 |
Preparing Stock Solutions
for Ropinirole
The following data is based on the product molecular weight 296.84
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.37 mL | 16.84 mL | 33.69 mL |
| 5 mM | 0.67 mL | 3.37 mL | 6.74 mL |
| 10 mM | 0.34 mL | 1.68 mL | 3.37 mL |
| 50 mM | 0.07 mL | 0.34 mL | 0.67 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Tulloch Pharmacologic profile of ropinirole: a nonergoline DA agonist. Neurology 1997 PMID: 9222275
- Eden Preclinical pharmacology of ropin. (SK&F 101468-A) a novel DA D2 agonist. Pharmacol.Biochem.Behav. 1991 PMID: 1673248
Product Specific Notices for Ropinirole
For research use only
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