35 results for "Cyclin-dependent Kinase Inhibitors Small Molecules and Peptides" in Products
Cyclin-dependent Kinase Inhibitors: Small Molecules and Peptides
What are Cyclins?
Cyclins are a heterogeneous family of proteins that have a common 100 amino acid sequence called the cyclin box. Their only cellular role is to activate CDKs, and their expression fluctuates throughout the cell cycle, dependent on the cell cycle phase they are involved in. There are several subfamilies of cyclins, and several 'orphan' cyclins for which no CDK binding partner has been identified.
CDK Structure & Localization
CDKs are constitutively expressed and range in size ...
| Alternate Names: | Palbociclib |
| Chemical Name: | 6-acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one isethionate salt |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 5-(6-Quinolinylmethylene)-2-[(2-thienylmethyl)amino]-4(5H)-thiazolone |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]-9H-purin-2-yl]amino]-1-butanol dihydrochloride |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | N-[1-[[3-[[(2E)-4-(Dimethylamino)-1-oxo-2-buten-1-yl]amino]phenyl]sulfonyl]-4-piperidinyl]-4-[(2,4,6- trichlorobenzoyl)amino]-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[(2-Phenylethyl)amino]-6-quinazolinecarbonitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | L 86-8275 |
| Chemical Name: | 2-(2-Chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methyl-4-piperidinyl]-4H-1-benzopyran-4-one hydrochloride |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | CYC 202,Seliciclib |
| Chemical Name: | (2R)-2-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[[[5'-Chloro-2'-[[trans-4-[[(1R)-2-methoxy-1-methylethyl]amino]cyclohexyl]amino][2,4'-bipyridin]-6-yl]amino]methyl]tetrahydro-2H-pyran-4-carbonitrile |
| Purity: | ≥97% (HPLC) |
| Alternate Names: | NG 95 |
| Chemical Name: | (2R)-2-[[6-[(3-Chloro-4-carboxyphenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | [4-Amino-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-5-pyrimidinyl](2,3-difluoro-6-methoxyphenyl)methanone |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 3-[[4-[2-[(3-Chlorophenyl)amino]-4-pyrimidinyl]-2-pyridinyl]amino]-1-propanol |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | LEE-011 |
| Chemical Name: | 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | SCH 727965 |
| Chemical Name: | (2S)-1-[3-Ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2-piperidineethanol |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 1,5,6,7-Tetrahydro-2-(4-pyridinyl)-4H-pyrrolo[3,2-c]pyridin-4-one hydrochloride |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2,2'-[[6-[[(4-Methoxyphenyl)methyl]amino]-9-(1-methylethyl)-9H-purin-2-yl]imino]bis[ethanol] |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-[2-Methyl-1-(1-methylethyl)-1H-imidazol-5-yl]-N-[4-(methylsulfonyl)phenyl]-2-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | NG 60 |
| Chemical Name: | (2R)-2-[[6-[(3-Chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | N-(1-((3-(4-(Dimethylamino)butanamido)phenyl)sulfonyl)piperidin-4-yl)-4-(2,4,6-trichlorobenzamido)-1H-pyrazole-3-carboxamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | N5-(6-Aminohexyl)-3-(1-methylethyl)-N7-(phenylmethyl)pyrazolo[1,5-a]pyrimidine-5,7-diamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | BMS-387032 |
| Chemical Name: | N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | AUZ 454 |
| Chemical Name: | N-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide |
| Purity: | ≥95% (HPLC) |
| Chemical Name: | N-(4-Butyl-2-methylphenyl)acetamide |
| Purity: | ≥98% (HPLC) |
