Antiviral Compounds Small Molecules and Peptides

Reverse transcriptase inhibitor

Potent inhibitor of SERCA ATPase

BLT1/BLT2 receptor agonist and potent chemotactic factor

Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation

α-glucosidase I and II inhibitor; also inhibits ceramide-specific glycosyltransferases and exhibits broad spectrum antiviral activity

Selective CCR5 antagonist

Inhibits hepatitis C viral life cycle; also α-crystallin (cryAB) chaperone

Selective inhibitor of Akt/PKB signaling. Antitumor and antiviral

Toll-like receptor 7 (TLR7) agonist

Potent and selective VPAC2 agonist

MRP and OAT3 inhibitor

Protein kinase inhibitor

Specific inhibitor of NF-κB activation

Antimicrobial peptide derivative of human cathelicidin

Non-selective P2 antagonist

Non-selective PI 3-kinase inhibitor

Toll-like receptor 7 (TLR7) agonist

Core binding factor inhibitor; attenuates hematopoiesis

mSTING agonist; induces antitumor immunological responses

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter

Potent HIV-1 protease inhibitor

Potent Aurora kinase B inhibitor

Potent CXCR4 antagonist

DNA polymerase α, δ and ε inhibitor