Skip to main content

33 results for "NMDA Receptor Antagonists" in Products

NMDA Receptor Antagonists Products

NMDA receptors are expressed alongside AMPA receptors on the postsynaptic membrane of excitatory synapses, where they initiate a two-component excitatory postsynaptic potential (EPSP). The activation of AMPA receptors produces a current that has rapid onset and decay, while activation of NMDA receptors leads to a current with slower onset and decay. The slow decay of NMDA-mediated currents is due to the slow dissociation of glutamate from NMDA receptors, compared with AMPA receptors. Unlike ...

Show More

Potent and selective NMDA receptor antagonist; more active form of DL-AP5

Alternate Names: 2-APV,D-APV,D-2-amino-5-phosphonovalerate
Chemical Name: D-(-)-2-Amino-5-phosphonopentanoic acid
Purity: ≥98% (HPLC)
Potent and selective NMDA receptor antagonist; more active form of DL-AP5

Non-competitive NMDA receptor antagonist

Chemical Name: 2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone hydrochloride
Purity: ≥99% (HPLC)
Non-competitive NMDA receptor antagonist

Potent and selective non-NMDA iGluR antagonist

Alternate Names: Cyanquixaline
Chemical Name: 6-Cyano-7-nitroquinoxaline-2,3-dione
Purity: ≥98% (HPLC)
Potent and selective non-NMDA iGluR antagonist

Non-competitive NMDA antagonist; acts at ion channel site

Alternate Names: Dizocilpine
Chemical Name: (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate
Purity: ≥98% (HPLC)
Non-competitive NMDA antagonist; acts at ion channel site

Potent and selective NMDA antagonist

Alternate Names: DL-APV
Chemical Name: DL-2-Amino-5-phosphonopentanoic acid
Purity: ≥98% (HPLC)
Potent and selective NMDA antagonist

GluN2B-selective NMDA antagonist

Chemical Name: RS)-α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate
Purity: ≥98% (HPLC)
GluN2B-selective NMDA antagonist

Potent and selective NMDA antagonist; sodium salt of DL-AP5

Chemical Name: DL-2-Amino-5-phosphonopentanoic acid sodium salt
Purity: ≥98% (HPLC)
Potent and selective NMDA antagonist; sodium salt of DL-AP5

Potent and selective NMDA antagonist; acts at glycine site

Alternate Names: PAMQX
Chemical Name: [(1S)-1-[[(7-Bromo-1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl]amino]ethyl]phosphonic acid hydrochloride
Purity: ≥98% (HPLC)
Potent and selective NMDA antagonist; acts at glycine site

NMDA antagonist; acts at ion channel site

Chemical Name: 3,5-Dimethyl-tricyclo[3.3.1.13,7]decan-1-amine hydrochloride
NMDA antagonist; acts at ion channel site

Highly potent NMDA antagonist

Chemical Name: trans-2-Carboxy-5,7-dichloro-4-phenylaminocarbonylamino-1,2,3,4-tetrahydroquinoline
Purity: ≥98% (HPLC)
Highly potent NMDA antagonist

GluN1/GluN2A-selective NMDA antagonist

Chemical Name: 3-Chloro-4-fluoro-N-[4-[[2-(phenylcarbonyl)hydrazino]carbonyl]benzyl]benzenesulfonamide
Purity: ≥98% (HPLC)
GluN1/GluN2A-selective NMDA antagonist

NMDA antagonist; less active enantiomer of (+)-MK 801

Chemical Name: (5R,10S)-(-)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cylcohepten-5,10-imine maleate
Purity: ≥98% (HPLC)
NMDA antagonist; less active enantiomer of (+)-MK 801

Potent competitive NMDA antagonist

Alternate Names: Midafotel,SDZ EAA 494
Chemical Name: D-4-[(2E)-3-Phosphono-2-propenyl]-2-piperazinecarboxylic acid
Potent competitive NMDA antagonist

Non-competitive NMDA antagonist; also σ ligand

Chemical Name: (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol hemi-(DL)-tartrate
Purity: ≥98% (HPLC)
Non-competitive NMDA antagonist; also σ ligand

Potent NMDA antagonist

Chemical Name: (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
Potent NMDA antagonist

GluN2C/GluN2D-selective NMDA antagonist

Chemical Name: (2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid
Purity: ≥98% (HPLC)
GluN2C/GluN2D-selective NMDA antagonist

Potent NMDA antagonist; more active enantiomer of (RS)-CPP

Chemical Name: 3-((R)-2-Carboxypiperazin-4-yl)-propyl-1-phosphonic acid
Potent NMDA antagonist; more active enantiomer of (RS)-CPP

NMDA antagonist; acts at glycine site

Chemical Name: 7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone
Purity: ≥98% (HPLC)
NMDA antagonist; acts at glycine site

Potent NMDA antagonist, acts at glycine site; sodium salt of 5,7-Dichlorokynurenic acid

Chemical Name: 5,7-Dichloro-4-hydroxyquinoline-2-carboxylic acid sodium salt
Purity: ≥98% (HPLC)
Potent NMDA antagonist, acts at glycine site; sodium salt of 5,7-Dichlorokynurenic acid

Potent and noncompetitive NMDA antagonist

Alternate Names: CNS 1102
Chemical Name: N-(3-Ethylphenyl)-N-methyl-N'-1-naphthalenylguanidine hydrochloride
Purity: ≥98% (HPLC)
Potent and noncompetitive NMDA antagonist

Potent competitive NMDA antagonist

Chemical Name: cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid
Potent competitive NMDA antagonist

Potent and selective NMDA antagonist

Chemical Name: (E)-(±)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid
Purity: ≥98% (HPLC)
Potent and selective NMDA antagonist

Potent and selective NMDA antagonist; less active form of DL-AP5

Chemical Name: L-(+)-2-Amino-5-phosphonopentanoic acid
Purity: ≥98% (HPLC)
Potent and selective NMDA antagonist; less active form of DL-AP5

GluN2C/GluN2D-selective NMDA antagonist

Chemical Name: 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid
Purity: ≥97% (HPLC)
GluN2C/GluN2D-selective NMDA antagonist

Non-competitive and GluN2C/GluN2D-selective NMDA antagonist

Chemical Name: 4-[6-Methoxy-2-[(1E)-2-(3-nitrophenyl)ethenyl]-4-oxo-3(4H)quinazolinyl]benzoic acid
Purity: ≥98% (HPLC)
Non-competitive and GluN2C/GluN2D-selective NMDA antagonist
Results Per Page
5 10 25 50
/ 2