CGS 19755
Tocris Bioscience, part of Bio-Techne | Catalog # 1241
Potent competitive NMDA antagonist
Key Product Details
Description
Potent competitive NMDA antagonist
Product Description
CGS 19755 is a potent, competitive NMDA receptor antagonist. Anticonvulsant and neuroprotective.Product Specifications
Molecular Weight
223.17
Formula
C7H14NO5P
Storage
Store at RT
Chemical Name
cis-4-[Phosphomethyl]-piperidine-2-carboxylic acid
CAS Number
110347-85-8
PubChem ID
6604838
InChI Key
LPMRCCNDNGONCD-NTSWFWBYSA-N
SMILES
O=P(C[C@@H]1C[C@H]([C@](O)=O)NCC1)(O)O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 5.58 | 25 |
Preparing Stock Solutions
for CGS 19755
The following data is based on the product molecular weight 223.17
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.25 mM | 17.92 mL | 89.62 mL | 179.24 mL |
| 1.25 mM | 3.58 mL | 17.92 mL | 35.85 mL |
| 2.5 mM | 1.79 mL | 8.96 mL | 17.92 mL |
| 12.5 mM | 0.36 mL | 1.79 mL | 3.58 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Lehmann CGS 19755, a selective and competitive N-MthD.-aspartate-type excitatory amino acid receptor antagonist. J.Pharmacol.Exp.Ther. 1988 PMID: 2899170
- Perez-Pinzon Correlation of CGS 19755 neuroprotection against in vivo excitotoxicity and focal cerebral ischemia. J.Cereb.Blood Flow Metab. 1995 PMID: 7673380
- Bennett Behavioral pharmacological profile of CGS 19755, a competitive antagonist at N-MthD.-aspartate receptors. J.Pharmacol.Exp.Ther. 1989 PMID: 2547931
Product Specific Notices for CGS 19755
For research use only
Loading...
Loading...