Small Molecules and Peptides (19)
Small Molecules (12)
Peptides (7)
Inhibitor (19)
5 (4)
3 & up (5)
Tocris Bioscience (19)
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19 results for "Integrin Receptor Inhibitors" in Products

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Integrin Receptor Inhibitors

GR 144053 trihydrochloride
Catalog #: 1263
Citations (11)
Product Documents
Images (1)

Glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic

Chemical Name:
4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride
Purity:
≥98%
Glycoprotein IIb/IIIa (integrin αIIbβ3) receptor antagonist. Antithrombotic
Catalog #
Availability
Size / Price
Qty
1263/50
1263/10
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BIO 1211
Catalog #: 3910
Citations (12)
Product Documents
Images (1)

Selective α4β1 (VLA-4) inhibitor

Purity:
≥95%
Selective α4β1 (VLA-4) inhibitor
Catalog #
Availability
Size / Price
Qty
3910/1
Bulk Order

BTT 3033
Catalog #: 4724
(1)
Citations (33)
Product Documents
Images (1)

Selective inhibitor of integrin α2β1

Chemical Name:
1-(4-Fluorophenyl)-N-methyl-N-[4[[(phenylamino)carbonyl]amino]phenyl]-1H-pyrazole-4-sulfonamide
Purity:
≥98%
Selective inhibitor of integrin α2β1
Catalog #
Availability
Size / Price
Qty
4724/50
4724/10
Bulk Order

RGDS peptide
Catalog #: 3498
(2)
Citations (40)
Product Documents
Images (1)

Integrin binding sequence; inhibits integrin receptor function

Purity:
≥95%
Integrin binding sequence; inhibits integrin receptor function
Catalog #
Availability
Size / Price
Qty
3498/10
Bulk Order

BOP
Catalog #: 6047
Citations (3)
Product Documents
Images (1)

Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs

Chemical Name:
N-(Benzenesulfonyl)-L-prolyl-L-O-(1-pyrrolidinylcarbonyl)tyrosine sodium salt
Purity:
≥98%
Dual α9β1/α4β1 integrin inhibitor; preferentially mobilizes HSCs
Catalog #
Availability
Size / Price
Qty
6047/10
Bulk Order

BIO 5192
Catalog #: 5051
(2)
Citations (22)
Product Documents
Images (1)

Highly potent and selective inhibitor of integrin α4β1 (VLA-4)

Chemical Name:
(2S)-2-[[[(2S)-1-[(3,5-Dichlorophenyl)sulfonyl]-2-pyrrolidinyl]carbonyl]amino]-4-[[(2S)-4-methyl-2-[methyl[2-[4-[[[(2-methylphenyl)amino]carbonyl]amino]phenyl]acetyl]amino]-1-oxopentyl]amino]butanoic acid
Purity:
≥98%
Highly potent and selective inhibitor of integrin α4β1 (VLA-4)
Catalog #
Availability
Size / Price
Qty
5051/10
5051/50
Bulk Order

TC-I 15
Catalog #: 4527
Citations (10)
Product Documents
Images (1)

Potent α2β1 inhibitor; displays antithrombotic activity in vivo

Chemical Name:
N-[[(4R)-5,5-Dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]-L-alanine
Purity:
≥98%
Potent α2β1 inhibitor; displays antithrombotic activity in vivo
Catalog #
Availability
Size / Price
Qty
4527/50
4527/10
Bulk Order

Obtustatin
Catalog #: 4664
(1)
Citations (11)
Product Documents
Images (1)

Potent and selective α1β1 inhibitor

Purity:
≥95%
Potent and selective α1β1 inhibitor
Catalog #
Availability
Size / Price
Qty
4664/100U
Bulk Order

Cilengitide
Catalog #: 5870
Citations (22)
Product Documents
Images (1)

Potent and selective inhibitor of integrins αvβ3 and αvβ5

Alternate Names:
EMD121974
Purity:
≥95%
Potent and selective inhibitor of integrins αvβ3 and αvβ5
Catalog #
Availability
Size / Price
Qty
5870/10
Bulk Order

ATN 161
Catalog #: 6058
Citations (11)
Product Documents
Images (1)

α5β1 integrin receptor antagonist

Purity:
≥95%
α5β1 integrin receptor antagonist
Catalog #
Availability
Size / Price
Qty
6058/10
Bulk Order

Echistatin, α1 isoform
Catalog #: 3202
Citations (2)
Product Documents
Images (1)

αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor

Purity:
≥95%
αVβ3 and glycoprotein IIb/IIIa (integrin αIIbβ3) inhibitor
Catalog #
Availability
Size / Price
Qty
3202/100U
Bulk Order

TCS 2314
Catalog #: 3900
Citations (4)
Product Documents
Images (1)

α4β1 (VLA-4) antagonist

Chemical Name:
1-[[(3S)-4-[2-[4-[[[(2-Methylphenyl)amino]carbonyl]amino]phenyl]acety]l-3-morpholinyl]carbonyl]-4-piperidinediacetic acid
Purity:
≥98%
α4β1 (VLA-4) antagonist
Catalog #
Availability
Size / Price
Qty
3900/10
3900/50
Bulk Order

A 286982
Catalog #: 4228
(1)
Citations (7)
Product Documents
Images (1)

Potent inhibitor of the LFA-1/ICAM-1 interaction

Chemical Name:
(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
Purity:
≥98%
Potent inhibitor of the LFA-1/ICAM-1 interaction
Catalog #
Availability
Size / Price
Qty
4228/10
4228/50
Bulk Order

A 286982
Catalog #: 4228
(1)
Citations (7)
Product Documents
Images (1)

Potent inhibitor of the LFA-1/ICAM-1 interaction

Chemical Name:
(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one
Purity:
≥98%
Potent inhibitor of the LFA-1/ICAM-1 interaction
Catalog #
Availability
Size / Price
Qty
4228/10
4228/50
Bulk Order

K34c
Catalog #: 5114
Citations (32)
Product Documents
Images (1)

Potent and selective α5β1 integrin inhibitor

Chemical Name:
N-(2,6-Dimethylbenzoyl)-O-[3-(2-pyridinylamino)propyl]-L-tyrosine
Purity:
≥98%
Potent and selective α5β1 integrin inhibitor
Catalog #
Availability
Size / Price
Qty
5114/5
Bulk Order

E 7820
Catalog #: 6785
Citations (1)
Product Documents
Images (1)

α2 integrin inhibitor; anti-angiogenic

Chemical Name:
3-Cyano-N-(3-cyano-4-methyl-1H-indol-7-yl)benzenesulfonamide
Purity:
≥98%
α2 integrin inhibitor; anti-angiogenic
Catalog #
Availability
Size / Price
Qty
6785/10
6785/50
Bulk Order

GLPG 0187
Catalog #: 7059
Citations (2)
Product Documents
Images (1)

Potent αv integrin inhibitor

Chemical Name:
3-[[2,5-Dimethyl-6-[4-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)-1-piperidinyl]-4-pyrimidinyl]amino]-N-[(4-methoxyphenyl)sulfonyl]-L-alanine
Purity:
≥97%
Potent αv integrin inhibitor
Catalog #
Availability
Size / Price
Qty
7059/10
7059/50
Bulk Order

EMD 527040 hydrochloride
Catalog #: 7508
Citations (2)
Product Documents
Images (1)

ανβ6 integrin inhibitor

Chemical Name:
N-[1-Oxo-5-(2-pyridinylamino)pentyl]-O-(phenylmethyl)-L-seryl-3-(3,5-dichlorophenyl)-β-alanine hydrochloride
Purity:
≥98%
ανβ6 integrin inhibitor
Catalog #
Availability
Size / Price
Qty
7508/5
Bulk Order

EMD 527040 hydrochloride
Catalog #: 7508
Citations (2)
Product Documents
Images (1)

ανβ6 integrin inhibitor

Chemical Name:
N-[1-Oxo-5-(2-pyridinylamino)pentyl]-O-(phenylmethyl)-L-seryl-3-(3,5-dichlorophenyl)-β-alanine hydrochloride
Purity:
≥98%
ανβ6 integrin inhibitor
Catalog #
Availability
Size / Price
Qty
7508/5
Bulk Order
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