A 286982

Tocris Bioscience, part of Bio-Techne | Catalog # 4228

Potent inhibitor of the LFA-1/ICAM-1 interaction
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Key Product Details

Description

Potent inhibitor of the LFA-1/ICAM-1 interaction

View all Integrin Receptor Inhibitors »

Product Description

A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays respectively).

Product Specifications

Molecular Weight

453.55

Formula

C24H27N3O4S

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one

CAS Number

280749-17-9

PubChem ID

9846729

InChI Key

HTGGAYLWTDOFDK-PKNBQFBNSA-N

SMILES

O=C(C)N1CCN(C(/C=C/C2=CC([N+]([O-])=O)=C(SC3=CC=CC=C3C(C)C)C=C2)=O)CC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 45.35 100
Ethanol 22.68 50

Preparing Stock Solutions for A 286982

The following data is based on the product molecular weight 453.55

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.20 mL 11.02 mL 22.05 mL
5 mM 0.44 mL 2.20 mL 4.41 mL
10 mM 0.22 mL 1.10 mL 2.20 mL
50 mM 0.04 mL 0.22 mL 0.44 mL

Calculators

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Product Documents for A 286982

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for A 286982

For research use only

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