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Histone Demethylase Inhibitors Products

Histone demethylases (KDMs), a family of enzymes, help catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues, which is catalyzed by histone methyltransferases.

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16 results for "Histone Demethylase Inhibitors" in Products

16 results for "Histone Demethylase Inhibitors" in Products

Histone Demethylase Inhibitors Products

Histone demethylases (KDMs), a family of enzymes, help catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues, which is catalyzed by histone methyltransferases.

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Pan-histone demethylase inhibitor

Chemical Name: 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone
Purity: ≥98% (HPLC)
Pan-histone demethylase inhibitor

Histone demethylase inhibitor; cell permeable

Alternate Names: 5-carboxy-8HQ
Chemical Name: 8-Hydroxy-5-quinolinecarboxylic acid
Purity: ≥98% (HPLC)
Histone demethylase inhibitor; cell permeable

Histone KDM inhibitor; cell permeable

Chemical Name: N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
Purity: ≥98% (HPLC)
Histone KDM inhibitor; cell permeable

JMJD1C inhibitor

Chemical Name: 8-Benzoyl-2,3,6,7-tetrahydro-5-oxo-5H-thiazolo[3,2-a]pyridine-6-acetic acid
Purity: ≥98% (HPLC)
JMJD1C inhibitor

Selective inhibitor of lysine demethylase 5

Chemical Name: 2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride
Purity: ≥98% (HPLC)
Selective inhibitor of lysine demethylase 5

Lysine-Specific Demethylase 1 (LSD1) inhibitor

Chemical Name: 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride
Purity: ≥98% (HPLC)
Lysine-Specific Demethylase 1 (LSD1) inhibitor

Pan Jumonji inhibitor; active in vivo

Chemical Name: 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine
Purity: ≥98% (HPLC)
Pan Jumonji inhibitor; active in vivo

Irreversible inhibitor of LSD1; also inhibits MAO

Alternate Names: 2-PCPA
Chemical Name: (±)-trans-2-Phenylcyclopropylamine hydrochloride
Purity: ≥98% (HPLC)
Irreversible inhibitor of LSD1; also inhibits MAO

Selective KDM2/7 inhibitor

Chemical Name: N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine
Purity: ≥98% (HPLC)
Selective KDM2/7 inhibitor

KDM4A/KDM4B inhibitor

Chemical Name: 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene
Purity: ≥98% (HPLC)
KDM4A/KDM4B inhibitor

LSD1 inhibitor

Chemical Name: 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride
Purity: ≥97% (HPLC)
LSD1 inhibitor

Potent JMJD3/UTX inhibitor

Chemical Name: N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine
Purity: ≥98% (HPLC)
Potent JMJD3/UTX inhibitor

Potent and selective LSD1 inhibitor

Chemical Name: rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine dihydrochloride
Purity: ≥98% (HPLC)
Potent and selective LSD1 inhibitor

LSD1 inhibitor

Chemical Name: (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride
Purity: ≥98% (HPLC)
LSD1 inhibitor

Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable

Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride
Purity: ≥98% (HPLC)
Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable

Inactive isomer of GSK J1 (Cat. No. 4593)

Chemical Name: N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester
Purity: ≥98% (HPLC)
Inactive isomer of GSK J1 (Cat. No. 4593)
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