16 results for "Histone Demethylase Inhibitors Small Molecules and Peptides" in Products
Histone Demethylase Inhibitors: Small Molecules and Peptides
Histone demethylases are a family of enzymes that includes lysine demethylases (KDMs) and arginine demethylases. These enzymes catalyze the removal of methyl groups from lysine and arginine residues on histone tails. They reverse the methylation of lysine and arginine residues that is catalyzed by histone methyltransferases.
The first histone demethylase to be discovered was lysine-specific demethylase 1 (LSD1), but further research identified an additional family of histone demethylases; ...
Pan-histone demethylase inhibitor
| Chemical Name: | 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
| Purity: | ≥98% (HPLC) |
Histone demethylase inhibitor; cell permeable
| Alternate Names: | 5-carboxy-8HQ |
| Chemical Name: | 8-Hydroxy-5-quinolinecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Irreversible inhibitor of LSD1; also inhibits MAO
| Alternate Names: | 2-PCPA |
| Chemical Name: | (±)-trans-2-Phenylcyclopropylamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Histone KDM inhibitor; cell permeable
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% (HPLC) |
Lysine-Specific Demethylase 1 (LSD1) inhibitor
| Chemical Name: | 4-[[4-[[[(1R,2S)-2-Phenylcyclopropyl]amino]methyl]-1-piperidinyl]methyl]benzoic acid dihydrochloride |
| Purity: | ≥98% (HPLC) |
Pan Jumonji inhibitor; active in vivo
| Chemical Name: | 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of lysine demethylase 5
| Chemical Name: | 2,4-Diisopropoxyphenyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective LSD1 inhibitor
| Chemical Name: | rel-N-[(1R,2S)-2-Phenylcyclopropyl]-4-piperidinamine dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent JMJD3/UTX inhibitor
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine |
| Purity: | ≥98% (HPLC) |
Selective KDM2/7 inhibitor
| Chemical Name: | N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine |
| Purity: | ≥98% (HPLC) |
KDM4A/KDM4B inhibitor
| Chemical Name: | 1,5-Bis[(1E)-2-(3,4-dichlorophenyl)ethenyl]-2,4-dinitrobenzene |
| Purity: | ≥98% (HPLC) |
LSD1 inhibitor
| Chemical Name: | 1-(4-methyl-1-piperazinyl)-2-[[(1R*,2S*)-2-[4-phenylmethoxy)phenyl]cyclopropyl]amino]ethanone dihydrochloride |
| Purity: | ≥97% (HPLC) |
LSD1 inhibitor
| Chemical Name: | (1R,2S)-rel-2-[3,5-Difluoro-2-(phenylmethoxy)phenyl]cycloprpanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
JMJD1C inhibitor
| Chemical Name: | 8-Benzoyl-2,3,6,7-tetrahydro-5-oxo-5H-thiazolo[3,2-a]pyridine-6-acetic acid |
| Purity: | ≥98% (HPLC) |
Inactive isomer of GSK J4 (Cat. No. 4594); cell permeable
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester hydrochloride |
| Purity: | ≥98% (HPLC) |
Inactive isomer of GSK J1 (Cat. No. 4593)
| Chemical Name: | N-[2-(3-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% (HPLC) |
