Skip to main content

21 results for "GTPase Inhibitors Small Molecules and Peptides" in Products

GTPase Inhibitors: Small Molecules and Peptides

Non-competitive dynamin inhibitor

Chemical Name: 3-Hydroxynaphthalene-2-carboxylic acid (3,4-dihydroxybenzylidene)hydrazide
Purity: ≥98% (HPLC)
Non-competitive dynamin inhibitor

Selective ARF6 inhibitor

Chemical Name: 3-(4-Chlorophenyl)-5-(4-nitrophenyl)-2-(phenylmethyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one
Purity: ≥98% (HPLC)
Selective ARF6 inhibitor

Potent farnesyl diphosphate (FPP) synthase inhibitor

Alternate Names: Zometa
Chemical Name: [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid
Purity: ≥98% (HPLC)
Potent farnesyl diphosphate (FPP) synthase inhibitor

Selective Cdc42 Rho family inhibitor

Alternate Names: CID 2950007
Chemical Name: 4-[4,5-Dihydro-5-(4-methoxyphenyl)-3-phenyl-1H-pyrazol-1-yl]benzenesulfonamide
Purity: ≥98% (HPLC)
Selective Cdc42 Rho family inhibitor

Dynamin I inhibitor

Chemical Name: 2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide
Purity: ≥98% (HPLC)
Dynamin I inhibitor

Selective inhibitor of Rac1-GEF interaction; antioncogenic

Chemical Name: N6-[2-[[4-(Diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-quinolinediamine trihydrochloride
Purity: ≥98% (HPLC)
Selective inhibitor of Rac1-GEF interaction; antioncogenic

Rho inhibitor

Chemical Name: D-Tryptophan (2E)-2-(6-quinoxalinylmethylene)hydrazide hydrochloride
Purity: ≥98% (HPLC)
Rho inhibitor

Gα-protein inhibitor; potent inhibitor of Gq/11 signaling

Chemical Name: (R)-1-((3S,6S,9S,12S,18R,21S,22R)-21-acetamido-18-benzyl-3-((R)-1-methoxyethyl)-4,9,10,12,16,22-hexamethyl-15-methylene-2,5,8,11,14,17,20-heptaoxo-1,19-dioxa-4,7,10,13,16-pentaazacyclodocosan-6-yl)-2-methylpropyl (2S,3R)-2-acetamido-3-hydroxy-4-methylpentanoate
Purity: ≥95% (HPLC)
Gα-protein inhibitor; potent inhibitor of Gq/11 signaling

Potent Rac family inhibitor

Chemical Name: 5-(5-(7-(Trifluoromethyl)quinolin-4-ylthio)pentyloxy)-2-(morpholinomethyl)-4H-pyran-4-one dihydrochloride
Purity: ≥98% (HPLC)
Potent Rac family inhibitor

DOCK2-Rac1 interaction inhibitor

Chemical Name: 4-[3-(2-Chlorophenyl)-2-propen-1-ylidene]-1-phenyl-3,5-pyrazolidinedione
Purity: ≥98% (HPLC)
DOCK2-Rac1 interaction inhibitor

Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Chemical Name: [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
Purity: ≥98% (HPLC)
Selectively kills mutant HRAS-expressing cells; glutathione peroxidase inhibitor; induces ferroptosis

Rac inhibitor

Chemical Name: N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine
Purity: ≥98% (HPLC)
Rac inhibitor

High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Chemical Name: 2-[4-[(2S)-2-(2-Phenyl-1H-benzimidazol-1-yl)-2-(4-piperidinyl)ethoxy]phenyl]-1-(phenylmethyl)-1H-benzimidazole trihydrochloride
Purity: ≥98% (HPLC)
High affinity PDEδ-KRas interaction inhibitor; binds to PDEδ

Selective Epac2 inhibitor

Chemical Name: 2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole
Purity: ≥98% (HPLC)
Selective Epac2 inhibitor

Geranylgeranyltransferase-I (GGTase-I) inhibitor

Chemical Name: (2R)-3,3,3-Trifluoro-2-methoxy-1-[(7R)-7-(2-methoxyphenyl)-3,9-diazaspiro[5.5]undec-3-yl]-2-phenyl-1-propanone hydrochloride
Purity: ≥98% (HPLC)
Geranylgeranyltransferase-I (GGTase-1) inhibitor

Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction

Chemical Name: 5-((1R,2S,5S)-2-(2-Chloro-3-fluorophenyl)-3-azabicyclo[3.1.0]hexan-3-yl)-N-((R,E)-4-(methylsulfonyl)but-3-en-2-yl)pyrazine-2-carboxamide
Purity: ≥98% (HPLC)
Potent covalent inhibitor of the RAS domain of the PI3K/p110α interaction

Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

Chemical Name: 3-(2,4-Dichloro-5-methoxyphenyl)-2,3-dihydro-2-thioxo-4(1H)-quinazolinone
Purity: ≥98% (HPLC)
Selective dynamin inhibitor; attenuates mitochondrial division and apoptosis

Epac inhibitor

Chemical Name: α-[(2-(3-Chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-3-isoxazolepropanenitrile
Purity: ≥98% (HPLC)
Epac inhibitor

Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable

Purity: ≥95% (HPLC)
Dynamin-related protein 1 (Drp1) inhibitor; cell-permeable

Epac2 inhibitor

Chemical Name: 1,3,5-Trimethyl-2-[(4-methylphenyl)sulfonyl]benzene
Purity: ≥98% (HPLC)
Epac2 inhibitor

Dynamin inhibitor; analog of dynasore (Cat. No. 2897)

Alternate Names: Dyngo 4a
Chemical Name: 3-Hydroxynaphthalene-2-carboxylic acid 2-[(2,4,5)-trihydroxyphenyl)methylene]hydrazide
Purity: ≥98% (HPLC)
Dynamin inhibitor; analog of dynasore (Cat. No. 2897)
Results Per Page
5 10 25 50
/ 1