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178 results for "ROCK1" in Products
ROCK1 Products
Rho-associated kinase I (ROCK1, ROK beta, p160ROCK) is a serine-threonine protein kinase and an effector of the small GTPase Rho. With N-terminus protein kinase domain and C-terminus Rho-binding domain/pleckstrin homology domain, ROCK1 can be activated by either RhoA or RhoB. In Rho specific ROCK1 activation, a Rho protein binds to the Rho-binding domain and induces a conformational change which opens the kinase domain for the phosphorylation of downstream effectors (1). Activated ROCK1 ...
GMP Version Available:
TB1254-GMP
GMP
Alternate Names:
y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor
Chemical Name:
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity:
≥98%
Chemical Name:
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity:
≥99%
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #701118
Applications:
WB
Reactivity:
Human, Mouse, Rat, Canine, Primate, +1 More
Details:
Mouse IgG Monoclonal Clone #154C1465
Applications:
WB, ICC/IF
![Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)BSA Free [NB100-56596]](https://resources.rndsystems.com/images/products/cleaved-ROCK1-Antibody-154C1465-Western-Blot-NB100-56596-img0004.jpg "Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)BSA Free [NB100-56596]")
Chemical Name:
(S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
Purity:
≥98%
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF, IP
![Western Blot: ROCK1 Antibody [NB100-624]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-NB100-624-img0003.jpg "Western Blot: ROCK1 Antibody [NB100-624]")
Reactivity:
Human, Mouse, Rat, Canine, Primate, +1 More
Details:
Mouse IgG Monoclonal Clone #154C1465
Applications:
WB, ICC/IF
![Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)Azide Free [NBP2-33238]](https://resources.rndsystems.com/images/products/cleaved-ROCK1-Antibody-154C1465-Azide-Free-Western-Blot-NBP2-33238-img0001.jpg "Western Blot: ROCK1 Antibody (154C1465)(active/cleaved)Azide Free [NBP2-33238]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, Mycoplasma
![Western Blot: ROCK1 Antibody [NBP1-82450]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-Western-Blot-NBP1-82450-img0008.jpg "Western Blot: ROCK1 Antibody [NBP1-82450]")
Reactivity:
Human, Mouse
Details:
Rabbit IgG Polyclonal
Applications:
KO, IHC, WB
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #261
Applications:
WB
![Western Blot: ROCK1 Antibody (261) [NBP2-42917]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-261-Western-Blot-NBP2-42917-img0005.jpg "Western Blot: ROCK1 Antibody (261) [NBP2-42917]")
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG2B Monoclonal Clone #464
Applications:
WB
![Western Blot: ROCK1 Antibody (464) [NBP2-42918]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-464-Western-Blot-NBP2-42918-img0004.jpg "Western Blot: ROCK1 Antibody (464) [NBP2-42918]")
Chemical Name:
N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
Purity:
≥98%
Reactivity:
Human
Details:
Mouse IgG1 kappa Monoclonal Clone #2E2
Applications:
WB, ELISA, ICC/IF
![Western Blot: ROCK1 Antibody (2E2) [H00006093-M01]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-2E2-Western-Blot-H00006093-M01-img0008.jpg "Western Blot: ROCK1 Antibody (2E2) [H00006093-M01]")
Alternate Names:
HA 1077
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ELISA, ICC/IF
![Western Blot: ROCK1 AntibodyBSA Free [NBP1-76569]](https://resources.rndsystems.com/images/products/ROCK1-Antibody-Western-Blot-NBP1-76569-img0001.jpg "Western Blot: ROCK1 AntibodyBSA Free [NBP1-76569]")
ROCK1 Antibody (23GB2065)
Catalog #:
NBP3-50245
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB2065
Applications:
WB, Flow, ICC/IF
ROCK1 Antibody (24GB5310)
Catalog #:
NBP3-50456
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #24GB5310
Applications:
WB, Flow, ICC/IF
ROCK1 Antibody (24GB4530)
Catalog #:
NBP3-50801
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #24GB4530
Applications:
WB, Flow, ICC/IF
Reactivity:
Human
Source:
Sf 9 (baculovirus)
Accession #:
NM_005406
Applications:
Bioactivity
Chemical Name:
N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]benzamide
Purity:
≥98%
Chemical Name:
(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
Purity:
≥98%
Chemical Name:
(3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride
Purity:
≥98%
Alternate Names:
Azaindole-1,BAY-549
Chemical Name:
6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
Purity:
≥98%
Alternate Names:
Azaindole-1,BAY-549
Chemical Name:
6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
Purity:
≥98%
Chemical Name:
2-Fluoro-N-[[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)phenyl]methyl]benzenemethanamine dihydrochloride
Purity:
≥98%
