Small Molecules and Peptides (13)
Small Molecules (13)
Inhibitor (12)
Other (1)
5 (4)
Tocris Bioscience (13)
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13 results for "RNA/DNA Polymerase Inhibitors" in Products

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RNA/DNA Polymerase Inhibitors

Tenofovir
Catalog #: 3666
(1)
Citations (3)
Product Documents
Images (1)

Reverse transcriptase inhibitor

Alternate Names:
PMPA,(R)-9-(2-Phosphonoylmethoxypropyl)adenine
Chemical Name:
(R)-[[2-(6-Amino-9H-purin-9-yl)-1-methylethoxy]methyl]phosphonic acid
Purity:
≥98%
Reverse transcriptase inhibitor
Catalog #
Availability
Size / Price
Qty
3666/10
3666/50
Bulk Order

Actinomycin D
Catalog #: 1229
(2)
Citations (121)
Product Documents
Images (1)

Inhibits RNA polymerase

Chemical Name:
2-Amino-(N,N)-1-bis(hexadecahydro-6,13-diisopropyl-2,5,9-trimethyl-1,4,7,11,14-pentaoxo-1H-pyrrolo[2,1]-[1,4,7,10,13] oxatetraazacyclohexadecin-10-yl)-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-dicarboxamide
Purity:
≥95%
Inhibits RNA polymerase
Catalog #
Availability
Size / Price
Qty
1229/10
Bulk Order

Mithramycin A
Catalog #: 1489
(1)
Citations (21)
Product Documents
Images (1)

Inhibitor of DNA and RNA polymerase

Chemical Name:
(1S)-5-Deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1.fwdarw.3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1.fwdarw.3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose
Purity:
≥95%
Inhibitor of DNA and RNA polymerase
Catalog #
Availability
Size / Price
Qty
1489/1
Bulk Order

Remdesivir
Catalog #: 7226
Citations (14)
Product Documents
Images (1)

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug

Alternate Names:
GS-5734
Chemical Name:
2-Ethylbutyl (2S)-2-[[(S)-[[(2R,3S,4R,5R)-5-(4-aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy]phenoxyphosphoryl]amino]propanoate
Purity:
≥98%
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleotide prodrug
Catalog #
Availability
Size / Price
Qty
7226/50
7226/10
Bulk Order

Aphidicolin
Catalog #: 5736
Citations (25)
Product Documents
Images (1)

DNA polymerase α, δ and ε inhibitor

Chemical Name:
(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11aH-cyclohepta[a]naphthalene-4,9-dimethanol
Purity:
≥98%
DNA polymerase α, δ and ε inhibitor
Catalog #
Availability
Size / Price
Qty
5736/1
Bulk Order

α-Amanitin
Catalog #: 4025
(1)
Citations (7)
Product Documents
Images (1)

Inhibitor of RNA polymerase II

Chemical Name:
cyclo[L-Asparaginyl-4-hydroxy-L-prolyl-(R)-4,5-dihydroxy-L-isoleucyl-6-hydroxy-2-mercapto-L-tryptophylglycyl-L-isoleucylglycyl-L-cysteinyl]cyclic (4→8)-sulfide (R)-S-oxide
Purity:
≥95%
Inhibitor of RNA polymerase II
Catalog #
Availability
Size / Price
Qty
4025/1
Bulk Order

BMH 21
Catalog #: 5417
Citations (3)
Product Documents
Images (1)

RNA polymerase I inhibitor; also p53 pathway activator

Chemical Name:
N-[2-(Dimethylamino)ethyl]-12-oxo-12H-benzo[g]pyrido[2,1-b]quinazoline-4-carboxamide
Purity:
≥98%
RNA polymerase I inhibitor; also p53 pathway activator
Catalog #
Availability
Size / Price
Qty
5417/50
5417/10
Bulk Order

Entecavir
Catalog #: 6234
Product Documents
Images (1)

Potent and selective hepatitis B virus inhibitor

Alternate Names:
BMS 200475,SQ 34676
Chemical Name:
2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
Purity:
≥98%
Potent and selective hepatitis B virus inhibitor
Catalog #
Availability
Size / Price
Qty
6234/10
6234/50
Bulk Order

Favipiravir
Catalog #: 7225
Citations (2)
Product Documents
Images (1)

Viral RNA polymerase inhibitor

Alternate Names:
T 705
Chemical Name:
6-Fluoro-3,4-dihydro-3-oxo-2-pyrazinecarboxamide
Purity:
≥98%
Viral RNA polymerase inhibitor
Catalog #
Availability
Size / Price
Qty
7225/50
Bulk Order

Galidesivir dihydrochloride
Catalog #: 7229
Product Documents
Images (1)

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral

Alternate Names:
BCX 4430
Chemical Name:
(2S,3S,4R,5R)-2-(4-Amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)-3,4-pyrrolidinediol dihydrochloride
Purity:
≥98%
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral
Catalog #
Availability
Size / Price
Qty
7229/2
Bulk Order

EIDD 1931
Catalog #: 7231
Product Documents
Images (1)

Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside

Chemical Name:
N-Hydroxycytidine
Purity:
≥98%
Viral RNA-dependent RNA polymerase (RdRP) inhibitor; broad spectrum antiviral nucleoside
Catalog #
Availability
Size / Price
Qty
7231/25
7231/5
Bulk Order

Emetine dihydrochloride
Catalog #: 7342
Citations (9)
Product Documents
Images (1)

RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika

Chemical Name:
(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolinyl]methyl]-2H-benzo[a]quinolizine dihydrochloride
Purity:
≥98%
RNA polymerase inhibitor; inhibits replication of a broad range of RNA and DNA viruses, including SARS-CoV-2 and Zika
Catalog #
Availability
Size / Price
Qty
7342/50
Bulk Order

Lopinavir
Catalog #: 7052
Citations (2)
Product Documents
Images (1)

Highly potent and selective HIV-1 protease inhibitor

Alternate Names:
ABT-378
Chemical Name:
(αS)-N-[(1S,3S,4S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2H)-pyrimidineacetamide
Purity:
≥98%
Highly potent and selective HIV-1 protease inhibitor
Catalog #
Availability
Size / Price
Qty
7052/50
Bulk Order
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