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11 results for "Retinoic Acid Receptor Agonists" in Products

Retinoic Acid Receptor Agonists Products

Retinoic acid receptors (RARs) are nuclear hormone receptors of the NR1B class, which function as heterodimers with retinoid X receptors (RXRs). There are three distinct RAR subtypes: RARα, RARβ and RARγ. RARα is present in most tissue types, whereas RARβ and RARγ expression is more selective.

RXR-RAR heterodimers act as ligand-dependent transcriptional regulators by binding to the specific retinoic acid response element (RARE) found in the promoter regions of ...

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Endogenous retinoic acid receptor agonist

Alternate Names: Tretinoin,ATRA
Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E,-nonatetraenoic acid
Purity: ≥98% (HPLC)
iPSC differentiation with retinoic acid
(2)

Retinoic acid synthesized to Ancillary Material Grade

Chemical Name: 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2E,4E,6E,8E-nonatetraenoic acid
Purity: ≥98%
Retinoic acid synthesized to Ancillary Material Grade

Retinoic acid analog; RARα agonist

Chemical Name: 4-[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carboxamido]benzoic acid
Purity: ≥98% (HPLC)
Retinoic acid analog; RARα agonist

Retinoic acid analog; RAR agonist

Alternate Names: Ro 13-7410
Chemical Name: 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid
Purity: ≥98% (HPLC)
Retinoic acid analog; RAR agonist

RARα agonist; anticancer agent

Alternate Names: Tamibarotene
Chemical Name: 4-[[(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)amino]carbonyl]benzoic acid
Purity: ≥98% (HPLC)
RARα agonist; anticancer agent

RARα-selective agonist

Chemical Name: 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]benzoic acid
Purity: ≥98% (HPLC)
RARα-selective agonist

Potent and selective RARγ agonist

Chemical Name: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid
Purity: ≥98% (HPLC)
Potent and selective RARγ agonist

Potent RAR agonist

Chemical Name: 4-[(1E)-3-[3,5-bis(1,1-Dimethylethyl)phenyl]-3-oxo-1-propenyl]benzoic acid
Purity: ≥98% (HPLC)
Potent RAR agonist

Selective RARβ agonist

Chemical Name: 5-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)-3-thiophenecarboxylic acid
Purity: ≥98% (HPLC)
Selective RARβ agonist

Selective RARγ agonist

Chemical Name: 3-Fluoro-4-[[2-hydroxy-2-(5,5,8,8-tetramethyl-5,6,7,8,-tetrahydro-2-naphthalenyl)acetyl]amino]-benzoic acid
Purity: ≥95% (HPLC)
Selective RARγ agonist

RARβ2 agonist

Chemical Name: 4-[4-(2-Butoxyethoxy-)-5-methyl-2-thiazolyl]-2-fluorobenzoic acid
Purity: ≥98% (HPLC)
RARβ2 agonist
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