10 results for "Protein Ser/Thr Phosphatase Inhibitors Small Molecules and Peptides" in Products
Protein Ser/Thr Phosphatase Inhibitors: Small Molecules and Peptides
Protein Ser/Thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by the hydrolysis of phosphoric acid monoesters. They directly oppose the actions of kinases and phosphorylases and therefore play an integral role in many signal transduction pathways.
There are two groups of serine/threonine phosphatases: phosphoprotein phosphatases (e.g. PP1, calcineurin), which are sensitive to okadaic acid; and metallo-phosphatases (e.g. ...
Inhibitor of calcineurin-mediated NFAT activation
| Alternate Names: | VIVIT peptide |
| Purity: | ≥95% (HPLC) |
Cell permeable NFAT inhibitor
| Alternate Names: | 11R-VIVIT |
| Purity: | ≥95% (HPLC) |
Potent calcineurin inhibitor; immunosuppressant
| Alternate Names: | Tacrolimus,Fujimycin |
| Chemical Name: | (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[(1E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)tetrone |
| Purity: | ≥98% (HPLC) |
Calcineurin inhibitor
| Alternate Names: | Ciclosporin A |
| Purity: | ≥98% (HPLC) |
Protein phosphatase 1 and 2A inhibitor
| Chemical Name: | N-[(3S)-[4-(1E)-3-[(2R,3R,4R,7S,8S,9R)-2-[(1S,3S,4S,5R,7E,9E,11E,13Z)-14-Cyano-3,5-dihydroxy-1-methoxy-4,6,8,9,13-pentamethyl-7,9,11,13-tetradecatetraenyl]-9-hydroxy-4,4,8-trimethyl-3-(phosphonooxy)-1,6-dioxaspiro[4.5]dec-7-yl]-1-propenyl]-2-oxazoly]butyl]-4-deoxy-4-(dimethylamino)-5-O-methyl-L-ribonamide |
| Purity: | ≥90% (HPLC) |
Selective inhibitor of eIF2α dephosphorylation
| Chemical Name: | 3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Inhibitor of the regulatory subunit PPP1R15A of protein phosphatase 1
| Chemical Name: | (2E)-2-[(2-Chlorophenyl)methylene]-hydrazinecarboximidamide carbonic acid salt |
| Purity: | ≥98% (HPLC) |
Cell-permeable inhibitor of eIF2α dephosphorylation
| Chemical Name: | 3--Phenyl-N-(2,2,2-trichloro-1-((((4-chlorophenyl)amino)carbonothioyl)amino)ethyl)acrylamide |
| Purity: | ≥98% (HPLC) |
DUSP6 and DUSP1 inhibitor
| Chemical Name: | 3-(Cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1H-inden-1-one |
| Purity: | ≥98% (HPLC) |
Protein phosphatase 1 and 2A inhibitor
| Chemical Name: | 9,10-Deepithio-9,10-didehydroacanthifolicin ammonium salt |
| Purity: | ≥98% (HPLC) |
