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20 results for "Other Degraders Small Molecules and Peptides" in Products
Other Degraders Small Molecules and Peptides
Selective peptide-based β-catenin Degrader (PROTAC®)
Purity:
≥95%
Potent MIF Degrader (PROTAC®)
Chemical Name:
8-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-N-(4-(7-hydroxy-2-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)octanamide
Purity:
≥98%
Potent PARP1 Degrader (PROTAC®)
Chemical Name:
N-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethyl)-12-(4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)methyl)benzoyl)piperazin-1-yl)-12-oxododecanamide
Purity:
≥98%
Mitochondrial targeting AUTAC Degrader
Chemical Name:
N-[(16R)-16-[[[2-Amino-9-[(4-fluorophenyl)methyl]-6,9-dihydro-6-oxo-1H-purin-8-yl]thio]methyl]-15,18-dioxo-4,7,10-trioxa-14,17-diazanonadec-1-yl]-α-oxo-2-phenyl-1H-indole-3-acetamide
Purity:
≥98%
Potent and selective USP7 Degrader (PROTAC®)
Chemical Name:
3-(1-(1-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)piperidine-4-carbonyl)piperidin-4-yl)-N-(3-((4-hydroxy-1-((R)-3-phenylbutanoyl)piperidin-4-yl)methyl)-4-oxo-3,4-dihydroquinazolin-7-yl)propanamide
Purity:
≥96%
Potent and selective nicotinamide phosphoribosyl transferase (NAMPT) Degrader (PROTAC®)
Chemical Name:
(2S,4R)-1-((S)-18-(tert-Butyl)-1,16-dioxo-1-(4-((4-((4-(3-(pyridin-3-ylmethyl)thioureido)phenyl)sulfonyl)piperazin-1-yl)methyl)phenyl)-5,8,11,14-tetraoxa-2,17-diazanonadecan-19-oyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide
Purity:
≥98%
Potent human carbonic anhydrase II Degrader (PROTAC®)
Chemical Name:
4-(Aminosulfonyl)-N-[12-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]dodecyl]benzamide
Purity:
≥98%
Potent hematopoietic prostaglandin D2 synthase Degrader (PROTAC®)
Chemical Name:
N-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-1-piperazinyl]carbonyl]-1-piperidinyl]phenyl]-2-phenoxy-5-pyrimidinecarboxamide
Purity:
≥98%
α-synuclein Degrader (PROTAC®)
Chemical Name:
2-[[3-[5-(1,3-Benzodioxol-5-yl)-1H-pyrazol-3-yl]phenyl]amino]-N-[2-[2-[2-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]ethoxy]ethoxy]ethyl]acetamide
Purity:
≥98%
Selective STING Degrader (PROTAC®)
Chemical Name:
(2E)-N1-[6-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]hexyl]-N4-[4-[[(5-nitro-2-furanyl)carbonyl]amino]phenyl]-2-butenediamide
Purity:
≥98%
Potent lactate dehydrogenase Degrader (PROTAC®)
Chemical Name:
2-(5-(Cyclopropylmethyl)-3-(3-(6-(13-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-13-oxotridecanamido)hex-1-yn-1-yl)phenyl)-4-(4-sulfamoylbenzyl)-1H-pyrazol-1-yl)thiazole-4-carboxylic acid
Purity:
≥98%
NSD2 Degrader (PROTAC®)
Chemical Name:
N-Cyclopropyl-N-(4-((5-(3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamido)propoxy)pyridin-2-yl)-carbamoyl)benzyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxamide
Purity:
≥98%
Potent and selective EED inhibitor
Chemical Name:
N-(2-Furanylmethyl)-8-[4-(methylsulfonyl)phenyl]-1,2,4-triazolo[4,3-c]pyrimidin-5-amine
Purity:
≥98%
Potent NSD2 Degrader
Chemical Name:
N-[[4-[[[2-(6-Amino-1-oxohexyl)-1,2,3,4-tetrahydro-6-isoquinolinyl]amino]carbonyl]phenyl]methyl]-N-cyclopropyl-3,4-dihydro-3-oxo-2H-1,4-benzoxazine-7-carboxamide trifluoroacetate
Purity:
≥98%
Negative control for Mpro 13b-K (Cat. No. 7228)
Chemical Name:
tert-Butyl (1-((R)-1-(((S)-4-(benzylamino)-3,4-dioxo-1-((S)-2-oxopyrrolidin-3-yl)butan-2-yl)amino)-3-cyclopropyl-1-oxopropan-2-yl)-2-oxo-1,2-dihydropyridin-3-yl)carbamate
Purity:
≥97%
PDEδ autophagy-tethering compound (ATTEC) Degrader
Chemical Name:
N-(6-(2-(2,6-Dibromo-4-((5-iodo-2-oxoindolin-3-ylidene)methyl)phenoxy)acetamido)hexyl)-4-(3,4-dimethyl-7-oxo-2-(p-tolyl)-2,7-dihydro-6H-pyrazolo[3,4-d]pyridazin-6-yl)butanamide
Purity:
≥98%
Potent and selective AR and AR L702H Degrader, orally bioavailable
Chemical Name:
4-[4-[4-[4-[[4-[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-7-methoxy-1-oxo-1H-isoindol-5-yl]-1-piperazinyl]methyl]-1-piperidinyl]phenyl]-1-piperidinyl]-3-fluoro-2-(trifluoromethyl)benzonitrile
Purity:
≥98%
MAGE-A3 Degrader (PROTAC®)
Chemical Name:
(2S,4R)-N-(2-(2-(2-(2-((4-(Furan-2-carbonyl)piperazin-1-yl)methyl)-4-(1H-indazol-4-yl)phenoxy)ethoxy)ethoxy)-4-(4-methylthiazol-5-yl)benzyl)-4-hydroxy-1-((S)-3-methyl-2-(1-oxoisoindolin-2-yl)butanoyl)pyrrolidine-2-carboxamide
Purity:
≥98%
Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins
Chemical Name:
N1-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-N7-((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)heptanediamide
Purity:
≥98%
Degrader (PROTAC®) of SNAP-tag™ labeled fusion proteins
Chemical Name:
N1-(4-(((2-Amino-6-chloropyrimidin-4-yl)oxy)methyl)benzyl)-N7-((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)heptanediamide
Purity:
≥98%