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11 results for "JAK Kinase Inhibitors Small Molecules and Peptides" in Products
JAK Kinase Inhibitors Small Molecules and Peptides
Potent JAK inhibitor
Alternate Names:
Tofacitinib citrate
Chemical Name:
(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrile citrate
Purity:
≥98%
JAK2/STAT3 signaling pathway inhibitor
Chemical Name:
(1R,5R,6R,7S)-rel-4-Oxo-8-(phenylmethyl)-8-azabicyclo[3.2.1]oct-2-ene-6,7-dicarboxylic acid 6,7-dimethyl ester
Purity:
≥98%
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
Alternate Names:
Tyrphostin AG 490
Chemical Name:
(E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide
Purity:
≥98%
JAK2, FLT3 and TrkA inhibitor; also inhibits AurA and AurB
Alternate Names:
CEP-701
Chemical Name:
(9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one
Purity:
≥98%
Potent and selective JAK1/JAK2 inhibitor; orally bioavailable
Alternate Names:
INCB018424
Chemical Name:
(3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile
Purity:
≥98%
Highly potent JAK1 and JAK2 inhibitor; also inhibits JAK3 and Tyk2
Alternate Names:
INCB 28050
Chemical Name:
1-(Ethylsulfonyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]-3-azetidineacetonitrile
Purity:
≥98%
JAK1-selective inhibitor
Chemical Name:
(3S,4R)-3-Ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)-1-pyrrolidinecarboxamide
Purity:
≥98%
Potent TYK2 inhibitor
Chemical Name:
2-Chloro-4-cyano-6-fluoro-N-[2-[[[(1R,2R)-2-fluorocyclopropyl]carbonyl]amino]-4-pyridinyl]benzamide
Purity:
≥98%
Potent and selective JAK3 inhibitor
Chemical Name:
1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malate
Purity:
≥98%
Potent pan-JAK inhibitor; induces intermediate mesoderm; cell-permeable
Alternate Names:
JAK inhibitor I
Chemical Name:
2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one
Purity:
≥98%
Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
Chemical Name:
(3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile phosphate
Purity:
≥98%
