Ruxolitinib phosphate

Tocris Bioscience, part of Bio-Techne | Catalog # 7048

Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor
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Key Product Details

Description

Phosphate salt of Ruxolitinib (Cat. No. 7064); potent and selective JAK1/JAK2 inhibitor

View all JAK Kinase Inhibitors »

Product Description

Ruxolitinib phosphate is a phosphate salt of Ruxolitinib (Cat. No. 7064). Potent and selective JAK1/JAK2 inhibitor; orally bioavailable.

Product Specifications

Molecular Weight

404.37

Formula

C17H18N6.H3O4P

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

(3R)-3-Cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile phosphate

CAS Number

1092939-17-7

PubChem ID

25127112

InChI Key

JFMWPOCYMYGEDM-XFULWGLBSA-N

SMILES

OP(O)(O)=O.N#CC[C@@H](N1C=C(C2=C3C=CNC3=NC=N2)C=N1)C4CCCC4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 40.44 100
Ethanol 4.04 10

Preparing Stock Solutions for Ruxolitinib phosphate

The following data is based on the product molecular weight 404.37

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.47 mL 12.36 mL 24.73 mL
5 mM 0.49 mL 2.47 mL 4.95 mL
10 mM 0.25 mL 1.24 mL 2.47 mL
50 mM 0.05 mL 0.25 mL 0.49 mL

Calculators

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Reconstitution Calculator

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Background References

References are publications that support the biological activity of the product.

Product Documents for Ruxolitinib phosphate

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Ruxolitinib phosphate

For research use only

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