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12 results for "Ion Channel Modulators" in Products

Ion Channel Modulators Products

Inhibits pacemaker (If) current

Alternate Names: ICI D7288
Chemical Name: 4-Ethylphenylamino-1,2-dimethyl-6-methylaminopyrimidinium chloride
Purity: ≥98% (HPLC)
Inhibits pacemaker (If) current

Mitochondrial VDAC modulator; also Ferroptosis activator

Chemical Name: 2-[1-[4-[2-(4-Chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone
Purity: ≥98% (HPLC)
Mitochondrial VDAC modulator; also Ferroptosis activator

Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic

Chemical Name: (±)-N-[4-[4-(Ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamide hemifumarate
Purity: ≥98% (HPLC)
Blocks IKr, hERG and L-type Ca2+ channels; class III antiarrhythmic

Binds voltage-dependent anion channel (VDAC)

Alternate Names: Olesoxime
Chemical Name: Cholest-4-en-3-one oxime
Purity: ≥98% (HPLC)
Binds voltage-dependent anion channel (VDAC)

Voltage-dependent anion channel (VDAC) inhibitor

Chemical Name: 1-(4-Chlorophenyl)-3-[4-[[4-(trifluoromethoxy)phenyl]amino]-1-piperidinyl]-2,5-pyrrolidinedione
Purity: ≥98% (HPLC)
Voltage-dependent anion channel (VDAC) inhibitor

Blocks sodium and potassium channels

Chemical Name: (S)-(6-Methoxyquinolin-4-yl)((2R,4S,8R)- 8-vinylquinuclidin-2-yl)methanol hydrochloride
Blocks sodium and potassium channels

Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)

Alternate Names: AD 810,CI 912
Chemical Name: 1,2-Benzisoxazole-3-methanesulfonamide
Purity: ≥99% (HPLC)
Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)

HCN channel blocker; inhibits If pacemaker current

Chemical Name: 3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride
Purity: ≥98% (HPLC)
HCN channel blocker; inhibits If pacemaker current

Blocks hyperpolarization-activated current (If)

Alternate Names: UL-FS 49
Chemical Name: 3-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-one hydrochloride
Purity: ≥98% (HPLC)
Blocks hyperpolarization-activated current (If)

Potent and selective HCN1 inhibitor

Chemical Name: 4-((2-Chloro-3-methylpyridin-4-yl)ethynyl)-5-methyl-1-(pyridin-3-yl)-1H-imidazole-2-carboxamide
Purity: ≥98% (HPLC)
Potent and selective HCN1 inhibitor

Inhibits glutamate release. Anticonvulsant

Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine
Purity: ≥99% (HPLC)
Inhibits glutamate release. Anticonvulsant

Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)

Chemical Name: 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate
Purity: ≥99% (HPLC)
Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)
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