Lamotrigine isethionate
Tocris Bioscience, part of Bio-Techne | Catalog # 2289
Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)
Key Product Details
Description
Inhibits glutamate release. Water-soluble salt of lamotrigine (Cat. No. 1611)
Product Description
Lamotrigine isethionate is a water-soluble salt of lamotrigine (Cat. No. 1611). Displays anticonvulsant effects and inhibits glutamate release, possibly through inhibition of Na+, K+ and Ca2+ currents.Licensing Information
Sold for research purposes under agreement from GlaxoSmithKlineProduct Specifications
Molecular Weight
382.22
Formula
C9H7Cl2N5.C2H6O4S
Storage
Desiccate at RT
Purity
≥99% (HPLC)
Chemical Name
6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine isethionate
CAS Number
113170-86-8
PubChem ID
45039646
InChI Key
CJIDZLNMKONKAD-UHFFFAOYSA-N
SMILES
OCCS(O)(=O)=O.NC1=NC(N)=C(N=N1)C1=CC=CC(Cl)=C1Cl
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Solubility
| Solvent | Max Conc. mg/mL | Max Conc. mM | |
|---|---|---|---|
| Solubility | |||
| water | 38.22 | 100 with gentle warming |
Preparing Stock Solutions
for Lamotrigine isethionate
The following data is based on the product molecular weight 382.22
Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 2.62 mL | 13.08 mL | 26.16 mL |
| 5 mM | 0.52 mL | 2.62 mL | 5.23 mL |
| 10 mM | 0.26 mL | 1.31 mL | 2.62 mL |
| 50 mM | 0.05 mL | 0.26 mL | 0.52 mL |
Calculators
Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Background References
References are publications that support the biological activity of the product.
- Grunze Modulation of calcium and potassium currents by lamotr. Neuropsychobiology 1998 PMID: 9778600
- Smith and Meldrum Cardioprotective effect of lamotr. after focal ischemia in rats. Stroke 1995 PMID: 7839380
- Zona and Avoli Lamotrigine reduces voltage-gated sodium currents in rat central neurons in culture. Epilepsia 1997 PMID: 9184596
- Leach Neurochemical and behavioral aspects of lamotr. Epilepsia 1991 PMID: 1685439
Product Specific Notices for Lamotrigine isethionate
For research use only
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