Dopamine D3 R/DRD3: Small Molecules and Peptides
DRD3 is the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. It is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variations may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing results in transcript variants encoding different isoforms. This variant represents the predominant transcript and encodes the longer isoform (a).
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13 results for "Dopamine D3 R/DRD3 Small Molecules and Peptides" in Products
13 results for "Dopamine D3 R/DRD3 Small Molecules and Peptides" in Products
Dopamine D3 R/DRD3: Small Molecules and Peptides
DRD3 is the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. It is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variations may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing results in transcript variants encoding different isoforms. This variant represents the predominant transcript and encodes the longer isoform (a).
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Caged dopamine; photolysed by UV light
| Purity: | ≥98% (HPLC) |
Dopamine precursor
| Alternate Names: | Levodopa |
| Chemical Name: | L-3,4-Dihydroxyphenylalanine |
| Purity: | ≥98% (HPLC) |
Potent and selective D2 and D3 antagonist
| Chemical Name: | 3,5-Dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide |
| Purity: | ≥98% (HPLC) |
D2-like agonist (D2>D3>D4)
| Chemical Name: | (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
High affinity D3 agonist (D3 ≥ D2 > D4)
| Chemical Name: | (4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benzopyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective D3 antagonist
| Chemical Name: | N-[(2E)-4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]-2-buten-1-yl]-4-(2-pyridyl)-benzamide dihydrochloride |
| Purity: | ≥98% |
Non-selective 5-HT, dopamine, adrenalin and histamine receptor antagonist; antipsychotic agent
| Chemical Name: | (3aR*,12bR*)-5-Chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole maleate |
| Purity: | ≥98% (HPLC) |
D2 and D3 agonist
| Alternate Names: | N 0923 |
| Chemical Name: | (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride |
| Purity: | ≥99% (HPLC) |
D2 and D3 antagonist (D3 > D2)
| Alternate Names: | (-)-Eticlopride |
| Chemical Name: | 3-Chloro-5-ethyl-N-[[(2S)-1-ethyl-2-pyrrolidinyl)methyl]-6-hydroxy-2-methoxy-benzamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective D3 agonist
| Chemical Name: | (S)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective D3 antagonist
| Chemical Name: | N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Selective D3 antagonist
| Chemical Name: | N-[trans-4-[2-(6-Cyano-3,4-dihydro-2(1H)-isoquinolinyl)ethyl]cyclohexyl]-4-quinolinecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% (HPLC) |
