Cyclooxygenase Inhibitors: Small Molecules and Peptides
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
11 results for "Cyclooxygenase Inhibitors Small Molecules and Peptides" in Products
11 results for "Cyclooxygenase Inhibitors Small Molecules and Peptides" in Products
Cyclooxygenase Inhibitors: Small Molecules and Peptides
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
| Chemical Name: | 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | Paracetamol |
| Chemical Name: | N-(4-Hydroxyphenyl)acetamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2-Acetoxybenzoic acid |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | SC 58635,Celebrex |
| Chemical Name: | 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
| Alternate Names: | SC 58236 |
| Chemical Name: | 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 4-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid |
| Purity: | ≥98% (HPLC) |
