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16 results for "Adenosine A2b R Small Molecules and Peptides" in Products

Adenosine A2b R: Small Molecules and Peptides

The Adenosine A2b Receptor (ADORA2B) gene codes for a receptor located on chromosome 17 (near the Smith-Magenis syndrome region) that initiates adenylyl cyclase in the presence of adenosine. The encoded adenoside receptor is 332 amino acids long, around 36 kDA, and is member to the G protein-coupled receptor superfamily and interacts with netrin-1 to promote axon elongation. ADORA2B has been associated with cholera, hepatitis B, breast cancer, carcinoma, eclampsia, ischemia, asthma, cystic fibrosis, astrocytoma, and atherosclerosis. It is involved in signal transduction IP3 signaling, GPCR ligand binding and signaling, and the methotrexate pathway through interactions with the EZR, NTN1, ADA, DDC, and SLC9A3R2 genes.

Endogenous adenosine receptor agonist

Chemical Name: 9-β-D-Ribofuranosyl-9H-purin-6-amine
Purity: ≥98% (HPLC)
Endogenous adenosine receptor agonist

High affinity adenosine agonist

Alternate Names: 5'-N-Ethylcarboxamidoadenosine
Chemical Name: 1-(6-Amino-9H-purin-9-yl)-1-deoxy-N-ethyl-β-D-ribofuranuronamide
Purity: ≥98% (HPLC)
High affinity adenosine agonist

PDE inhibitor (non-selective)

Chemical Name: 3,7-Dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
PDE inhibitor (non-selective)

Potent and highly selective A2A antagonist

Chemical Name: 4-(2-[7-Amino-2-(2-furyl)[1,2,4]triazolo[2,3-a][1,3,5]triazin-5-ylamino]ethyl)phenol
Purity: ≥98% (HPLC)
Potent and highly selective A2A antagonist

Potent partial A2B agonist; cardioprotective

Chemical Name: 2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide
Purity: ≥98% (HPLC)
Potent partial A2B agonist; cardioprotective

Potent adenosine receptor antagonist

Chemical Name: 9-Chloro-2-(2-furanyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
Purity: ≥98% (HPLC)
Potent adenosine receptor antagonist

Potent adenosine A2A and A2B receptor partial agonist

Chemical Name: 2-Amino-4-(4-hydroxyphenyl)-6-[(1H-imidazol-2-ylmethyl)thio]-3,5-pyridinecarbonitrile
Purity: ≥98% (HPLC)
Potent adenosine A2A and A2B receptor partial agonist

Selective A2B antagonist

Chemical Name: N-(4-Cyanophenyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide
Purity: ≥98% (HPLC)
Selective A2B antagonist

Selective human A2B antagonist; water-soluble

Chemical Name: 4-(2,3,6,7-Tetrahydro-2,6-dioxo-1-propyl-1H-purin-8-yl)-benzenesulfonic acid
Purity: ≥98% (HPLC)
Selective human A2B antagonist; water-soluble

A1 and A2B antagonist. CNS stimulant

Chemical Name: 3,7-Dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
A1 and A2B antagonist. CNS stimulant

Adenosine receptor antagonist

Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid
Purity: ≥98% (HPLC)
Adenosine receptor antagonist

Highly selective A2B antagonist

Chemical Name: 8-[4-[4-(4-Chlorophenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine
Purity: ≥98% (HPLC)
Highly selective A2B antagonist

Adenosine receptor agonist

Alternate Names: 2-CADO
Chemical Name: 6-Amino-2-chloropurine riboside
Purity: ≥98% (HPLC)
Adenosine receptor agonist

Adenosine receptor antagonist

Alternate Names: Xanthine amine congener
Chemical Name: N-(2-Aminoethyl)-2-[4-(2,3,6,7-tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetamide dihydrochloride
Purity: ≥98% (HPLC)
Adenosine receptor antagonist

Selective A2B antagonist

Chemical Name: 8-[4-[4-(4-Chlorobenzyl)piperazide-1-sulfonyl)phenyl]]-1-propylxanthine
Purity: ≥98% (HPLC)
Selective A2B antagonist

Selective A2B antagonist

Alternate Names: CVT 6883
Chemical Name: 3-Ethyl-3,9-dihydro-1-propyl-8-[1-[[3-(trifluoromethyl)phenyl]methyl]-1H-pyrazol-4-yl]-1H-purine-2,6-dione
Purity: ≥98% (HPLC)
Selective A2B antagonist
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