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10 results for "Secretase Inhibitors Small Molecules and Peptides" in Products
Secretase Inhibitors Small Molecules and Peptides
γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling
Chemical Name:
(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity:
≥99%
γ-secretase inhibitor; induces neuronal differentiation
Alternate Names:
γ-Secretase Inhibitor XXI
Chemical Name:
N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity:
≥98%
DAPT synthesized to Ancillary Material Grade
Chemical Name:
(2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenylglycine 1,1-dimethylethyl ester
Purity:
≥99%
Potent and selective γ-secretase inhibitor
Alternate Names:
L 458,γ-Secretase Inhibitor X
Chemical Name:
(5S)-(tert-Butoxycarbonylamino)-6-phenyl-(4R)-hydroxy-(2R)-benzylhexanoyl)-L-leucy-L-phenylalaninamide
Purity:
≥97%
γ-secretase inhibitor; inhibits Notch pathway
Alternate Names:
Dibenzazepine,YO-01027
Chemical Name:
N-[(1S)-2-[[(7S)-6,7-Dihydro-5-methyl-6-oxo-5H-dibenz[b,d]azepin-7-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity:
≥98%
Potent γ-secretase inhibitor
Chemical Name:
2-[(1R)-1-[[(4-Chlorophenyl)sulfonyl](2,5-difluorophenyl)amino]ethyl-5-fluorobenzenebutanoic acid
Purity:
≥98%
γ-secretase inhibitor; attenuates amyloid plaque deposition
Chemical Name:
N-[cis-4-[(4-Chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexyl]-1,1,1-trifluoromethanesulfonamide
Purity:
≥98%
Potent γ-secretase inhibitor
Chemical Name:
(2S)-2-[[(2S)-6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthalenyl]amino]-N-[1-[2-[(2,2-dimethylpropyl)amino]-1,1-dimethylethyl]-1H-imidazol-4-yl]pentanamide dihydrobromide
Purity:
≥98%
Highly potent γ-secretase inhibitor; orally bioavailable
Alternate Names:
BMS-708163
Chemical Name:
(2R)-2-[[(4-Chlorophenyl)sulfonyl][[2-fluoro-4-(1,2,4-oxadiazol-3-yl)phenyl]methyl]amino]-5,5,5-trifluoropentanamide
Purity:
≥98%
Neuroprotective and neurotrophic compound; reduces Aβ40 and Aβ42 levels
Chemical Name:
2,2,2-Trifluoroacetic acid 1-(2,4-Dimethylphenyl)-2-[(3-methoxyphenyl)methylene]hydrazide
Purity:
≥98%
