9 results for "Histone Deacetylase 1/HDAC1 Small Molecules and Peptides" in Products
Histone Deacetylase 1/HDAC1: Small Molecules and Peptides
Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Histone deacetylase inhibitor
| Alternate Names: | 4-PB,Sodium phenylbutyrate |
| Chemical Name: | 4-Phenylbutyric acid, sodium salt |
| Purity: | ≥98% (HPLC) |
Histone deacetylase inhibitor
| Alternate Names: | VPA,Sodium Valproate |
| Chemical Name: | Sodium 2-propylpentanoate |
Selective HDAC3 inhibitor; also myelination inducer
| Chemical Name: | N-(2-Aminophenyl)-5-[(phenylmethyl)amino]-2-pyrazinecarboxamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Potent histone deacetylase inhibitor
| Chemical Name: | (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide |
| Purity: | ≥95% (HPLC) |
Pan-histone deacetylase inhibitor
| Chemical Name: | (2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Purity: | ≥98% (HPLC) |
Class I and II HDAC inhibitor
| Alternate Names: | Vorinostat |
| Chemical Name: | N-Hydroxy-N'-phenyloctanediamide |
| Purity: | ≥98% (HPLC) |
HDAC (Class I) inhibitor
| Alternate Names: | entinostat,SNDX 275 |
| Chemical Name: | (Pyridin-3-yl)methyl 4-(2-aminophenylcarbamoyl)benzylcarbamate |
| Purity: | ≥98% (HPLC) |
Potent class I and IIb HDAC inhibitor
| Chemical Name: | 5-[(4-[1,1'-Biphenyl]-4-yl-1,6-dihydro-6-oxo-2-pyrimidinyl)thio]-N-hydroxypentanamide |
| Purity: | ≥98% (HPLC) |
Selective class I HDAC Degrader (PROTAC®)
| Chemical Name: | (2S,4R)-1-((S)-2-(2-((9-(2-((4-((2-Aminophenyl)carbamoyl)phenyl)amino)-2-oxoethoxy)nonyl)oxy)acetamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide |
| Purity: | ≥97% (HPLC) |
