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98 results for "GSK-3 alpha/beta" in Products
GSK-3 alpha/beta Products
GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.
GMP Version Available:
TB4423-GMP
GMP
Alternate Names:
CHIR99021,CT99021
Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #SY26-05
Applications:
IHC, WB, ICC/IF, IP
Reactivity:
Human, Mouse, Rat, Porcine, Bovine, +5 More
Details:
Mouse IgG2B Monoclonal Clone #1H8
Applications:
IHC, WB, ICC/IF
![Western Blot: GSK-3 alpha/beta Antibody (1H8) [NB110-85523]](https://resources.rndsystems.com/images/products/GSK-3-alpha-beta-Antibody-1H8-Western-Blot-NB110-85523-img0003.jpg "Western Blot: GSK-3 alpha/beta Antibody (1H8) [NB110-85523]")
Chemical Name:
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Purity:
≥98%
Chemical Name:
3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
Purity:
≥98%
Reactivity:
Human, Mouse
Details:
Mouse IgG2B Monoclonal Clone #833916
Applications:
WB, ICC/IF
Alternate Names:
6BIO
Chemical Name:
(2'Z,3'E)-6-Bromoindirubin-3'-oxime
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Assay Range:
156-10000 pg/mL
Applications:
ELISA
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB4380
Applications:
WB, Flow, ICC/IF, Mycoplasma
![GSK-3 alpha/beta [p Tyr279] Antibody (23GB4380)](https://resources.rndsystems.com/images/products/nbp3-51276_-immunocytochemistry-immunofluorescence-639228358978800128.png "Immunocytochemistry/ Immunofluorescence: GSK-3 alpha/beta [p Tyr279] Antibody (23GB4380)[NBP3-51276] -")
GSK-3 alpha/beta Antibody (23GB1100)
Catalog #:
NBP3-51961
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB1100
Applications:
WB, Flow, ICC/IF, Mycoplasma
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #SR1908
Applications:
IHC, WB, ICC/IF, IP
Chemical Name:
9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Purity:
≥98%
Chemical Name:
2-Methyl-5-[3-[4-(methylsulfinyl)phenyl]-5-benzofuranyl]-1,3,4-oxadiazole
Purity:
≥98%
Chemical Name:
N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea
Purity:
≥98%
Chemical Name:
1-(7-Methoxyquinolin-4-yl)-3-[6-(trifluoromethyl)pyridin-2-yl]urea
Purity:
≥98%
Alternate Names:
NP 01139
Chemical Name:
2-Methyl-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione
Purity:
≥98%
Chemical Name:
3-Amino-6-(4-((4-(4-(1-(17-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaheptadecyl)-1H-1,2,3-triazol-4-yl)butyl)piperazin-1-yl)sulfonyl)phenyl)-N-(pyridin-3-yl)pyrazine-2-carboxamide
Purity:
≥98%
Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥97%
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, ELISA, IP
![Western Blot: GSK-3 alpha/beta [p Ser21] AntibodyAzide and BSA Free [NBP3-05443]](https://resources.rndsystems.com/images/products/GSK-3-alpha-beta-[p-Ser21]-Antibody-Western-Blot-NBP3-05443-img0003.jpg "Western Blot: GSK-3 alpha/beta [p Ser21] AntibodyAzide and BSA Free [NBP3-05443]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF