GR/NR3C1: Small Molecules and Peptides
Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.
9 results for "GR/NR3C1 Small Molecules and Peptides" in Products
9 results for "GR/NR3C1 Small Molecules and Peptides" in Products
GR/NR3C1: Small Molecules and Peptides
Glucocorticoid receptor (GR; NR3C1) is a member of the steroid receptor family. GR are expressed in almost all human tissues and organs. GR bind to its sequences as a homodimer. Two different forms, GR-alpha and GR-beta, differing in their C-terminal parts were isolated. GR-alpha is the classic GR that binds to glucocorticoids and transactivates or transrepresses glucocorticoid-responsive promoters. GR-beta does not bind glucocorticoids.
Anti-inflammatory glucocorticoid
| Chemical Name: | (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methyl-pregna-1,4-diene-3,20-dione |
| Purity: | ≥98% (HPLC) |
Adrenal glucocorticoid; immunosuppressant
| Chemical Name: | 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione |
| Purity: | ≥98% (HPLC) |
Progesterone and glucocorticoid receptor antagonist
| Alternate Names: | RU 486,RU 38486 |
| Chemical Name: | (11β,17β)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)-estra-4,9-dien-3-one |
| Purity: | ≥98% (HPLC) |
Selective high affinity glucocorticoid receptor agonist
| Chemical Name: | (6α,11β,16α,17α)-6,9-Difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid fluoromethyl ester |
| Purity: | ≥98% (HPLC) |
Glucocorticoid receptor agonist
| Chemical Name: | N-[4-[1-(4-Fluorophenyl)-1H-indazol-5-yl-3-(trifluoromethyl)phenyl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
Glucocorticoid receptor agonist
| Chemical Name: | 11β,17β,21-Trihydroxy-6α-methyl-1,4-pregnadiene-3,20-dione |
| Purity: | ≥98% (HPLC) |
Synthetic glucocorticoid; anti-inflammatory and chemopreventive
| Chemical Name: | (11β,16α)-16,17-[Butylidenebis(oxy)]-11,21-dihydroxypregna-1,4-diene-3,20-dione |
| Purity: | ≥98% (HPLC) |
Endogenous glucocorticoid
| Chemical Name: | (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione |
| Purity: | ≥98% (HPLC) |
Dexamethasone synthesized to Ancillary Material Grade
| Chemical Name: | (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione |
| Purity: | ≥98% |
