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252 results for "GDNF" in Products
GDNF Products
GDNF (Glial Cell Line-derived Neurotrophic Factor) is a secreted protein that promotes the survival of motoneurons, midbrain dopaminergic neurons, Purkinje cells, and sympathetic neurons. It is produced by Sertoli cells, type 1 astrocytes, Schwann cells, neurons, pinealocytes, and skeletal muscle cells. GDNF binding to GFR alpha 1 induces the recruitment of Ret, NCAM-1/CD56, various integrins, Syndecan-3, or N-Cadherin. GDNF-based therapies show promise in several neurodegenerative disorders, particularly Parkinson’s disease.
GMP Version Available:
212-GMP
GMP
Reactivity:
Human
Source:
NS0
Accession #:
P39905
Applications:
Binding Activity, Bioactivity
Reactivity:
Human
Source:
NS0
Accession #:
P39905.1
Applications:
Binding Activity, Bioactivity
Reactivity:
Human
Assay Range:
4.69-300 pg/mL (Cell Culture Supernates, Cell Lysates, Tissue Lysates, Serum, Plasma, EDTA Plasma, Heparin Plasma)
Applications:
ELISA
Reactivity:
Human, Rat
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N
Reactivity:
Rat
Source:
Sf 21 (baculovirus)
Accession #:
Q07731
Applications:
Binding Activity, Bioactivity
Reactivity:
Human
Assay Range:
31.2-2000 pg/mL
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #27106
Applications:
WB, ELISA(Cap)
Reactivity:
Human
Details:
Goat IgG Polyclonal
Applications:
WB, ELISA(Det)
Reactivity:
Human, Rat
Details:
Goat IgG Polyclonal
Applications:
WB, B/N
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #11D2
Applications:
IHC, WB, ELISA, Flow, IP
Reactivity:
Human
Source:
E. coli
Accession #:
NP_000505.1
Applications:
Bioactivity
Reactivity:
Human
Source:
E. coli
Accession #:
NP_000505.1
Applications:
Bioactivity
GMP Version Available:
BT-GDNF-GMP
GMP
Reactivity:
Human
Source:
E. coli
Accession #:
NP_000505.1
Applications:
Bioactivity
Reactivity:
Human
Source:
E. coli
Accession #:
P39905.1
Applications:
Bioactivity
Reactivity:
Human, Rat
Details:
Goat IgG Polyclonal
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #27165
Applications:
ICC/IF
Reactivity:
Human
Details:
Mouse IgG2B Monoclonal Clone #27109
Applications:
ELISA
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #27106R
Applications:
ELISA(Cap)
Reactivity:
Mouse
Source:
E. coli
Applications:
Bioactivity
Reactivity:
Human
Reactivity:
Human, Rat
Details:
Goat IgG Polyclonal
Applications:
IHC, WB, B/N