Complement Component C5aR1: Small Molecules and Peptides
Human complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 alpha chain. Human C5a has four alpha-helices plus three intrachain disulfide bonds that create a triple-loop structure.
Products:
4 results for "Complement Component C5aR1 Small Molecules and Peptides" in Products
4 results for "Complement Component C5aR1 Small Molecules and Peptides" in Products
Complement Component C5aR1: Small Molecules and Peptides
Human complement 5a (C5a) is an enzymatically generated glycoprotein that belongs to a family of structurally and functionally related proteins known as anaphylatoxins. C5a is a 74 amino acid (aa) peptide that is created by the activity of C5a convertase on the C5 alpha chain. Human C5a has four alpha-helices plus three intrachain disulfide bonds that create a triple-loop structure.
Products:
Potent C5a receptor peptide antagonist
| Purity: | ≥95% (HPLC) |
Potent C5a receptor antagonist
| Purity: | ≥95% (HPLC) |
High affinity C5a receptor antagonist
| Chemical Name: | N-[[4-(Dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent, selective human C5a receptor negative allosteric modulator (NAM)
| Chemical Name: | N,N-Bis(1,3-benzodioxol-5-ylmethyl)-1-butyl-2,4-diphenyl-1H-Imidazole-5-methanamine |
| Purity: | ≥98% (HPLC) |
