19 results for "CHRM4" in Products
CHRM4 Products
Muscarinic acetylcholine receptor M4 is an Acetylcholine Receptor. Unlike muscarinic receptor M2, the M4 receptor is not involved in smooth muscle contraction. The clinical relevance of this receptor is unknown. However, mouse studies have linked it to adenylyl cyclase inhibition. Muscarinic acetylcholine receptor M4 has been reported to be expressed in many regions of the rat brain, particularly the striatum and hippocampus. ESTs have been isolated from human breast and eye libraries.
| Reactivity: | Human, Rat, Bovine, Porcine, Equine, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free [NLS220]](https://resources.bio-techne.com/images/products/Muscarinic-Acetylcholine-Receptor-M4-CHRM4-Antibody-Immunohistochemistry-Paraffin-NLS220-img0002.jpg "Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M4/CHRM4 Antibody - BSA Free [NLS220]")
Selective M2 antagonist
| Alternate Names: | Otenzepad |
| Chemical Name: | 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% (HPLC) |
Functionally biased muscarinic M4 receptor agonist
| Chemical Name: | 3-[4-(Hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methylpyridine oxalate |
| Purity: | ≥98% (HPLC) |
Muscarinic agonist
| Chemical Name: | (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Rat, Porcine |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
Muscarinic agonist
| Chemical Name: | 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of M4 receptors
| Alternate Names: | ML 108 |
| Chemical Name: | 3-Amino-N-(4-methoxybenzyl)-4,6-dimethylthieno[2,3-b]pyridine carboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Rat, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #18C7.2 |
| Applications: | IHC, WB, IP |
Potent M2/M4 antagonist
| Chemical Name: | N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent and selective M4 mAChR antagonist
| Chemical Name: | (3aR,5s,6aS)-2-((Tetrahydro-2H-pyran-4-yl)methyl)-N-(6-(2,3,5-trifluorophenyl)pyridazin-3-yl)octahydrocyclopenta[c]pyrrol-5-amine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective M1 muscarinic agonist
| Chemical Name: | 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride |
| Purity: | ≥99% (HPLC) |
Selective positive allosteric modulator of M4 receptors; active in vivo; antipsychotic
| Chemical Name: | 3-Amino-5-chloro-N-cyclopropyl-6-methoxy-4-methylthieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Selective M4 antagonist
| Chemical Name: | 3,6a,11,14-Tetrahydro-9-methoxy-2-methyl-(12H)-isoquino[1,2-b]pyrrolo[3,2-f][1,3]benzoxazine-1-carboxylic acid, ethyl ester |
| Purity: | ≥98% (HPLC) |
Selective positive allosteric modulator of M4 receptors
| Chemical Name: | 3-Amino-N-[(4-chlorophenyl)methyl]-4,6-dimethylthieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of M2 and M4 receptors
| Chemical Name: | 3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
High affinity and selective M2 antagonist
| Chemical Name: | 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% (HPLC) |
| Applications: | WB |
![Western Blot: Muscarinic Acetylcholine Receptor M4/CHRM4 Overexpression Lysate [NBP2-04174]](https://resources.bio-techne.com/images/products/Muscarinic-Acetylcholine-Receptor-M4-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-04174-img0001.jpg "Western Blot: Muscarinic Acetylcholine Receptor M4/CHRM4 Overexpression Lysate [NBP2-04174]")
| Applications: | AP |