TAK1: Small Molecules and Peptides
TGF-beta-activated kinase 1 (TAK1; also MAP3K7) is a member of the STE Ser/Thr protein kinase family and the MAP kinase kinase kinase subfamily. Human TAK1 is 606 amino acids (aa) in length and contains a protein kinase domain at aa 36-291. There are three isoforms for TAK1. Isoform 1B is the largest isoform. Isoform 1A has a 27 aa deletion corresponding to aa 404-430 in isoform 1B, and isoform 1C has an 88 aa deletion corresponding to aa 519-606 in isoform 1B. TAK1 activity has been implicated during TGF beta-induced and Ras-dependent tumorigenesis.
3 results for "TAK1 Small Molecules and Peptides" in Products
3 results for "TAK1 Small Molecules and Peptides" in Products
TAK1: Small Molecules and Peptides
TGF-beta-activated kinase 1 (TAK1; also MAP3K7) is a member of the STE Ser/Thr protein kinase family and the MAP kinase kinase kinase subfamily. Human TAK1 is 606 amino acids (aa) in length and contains a protein kinase domain at aa 36-291. There are three isoforms for TAK1. Isoform 1B is the largest isoform. Isoform 1A has a 27 aa deletion corresponding to aa 404-430 in isoform 1B, and isoform 1C has an 88 aa deletion corresponding to aa 519-606 in isoform 1B. TAK1 activity has been implicated during TGF beta-induced and Ras-dependent tumorigenesis.
Potent and selective TAK1 MAPKKK inhibitor
| Chemical Name: | (3S,5Z,8S,9S,11E)-3,4,9,10-tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione |
| Purity: | ≥98% (HPLC) |
Potent and selective TAK1/MAP3K7 kinase inhibitor
| Chemical Name: | N1-(1-Propyl-1H-benzimidazol-2-yl)-1,3-benzenedicarboxamide |
| Purity: | ≥98% (HPLC) |
TGF-β-activated kinase (TAK1) inhibitor
| Chemical Name: | N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)benzamide |
| Purity: | ≥98% (HPLC) |
