6 results for "SCN11A Small Molecules and Peptides" in Products
SCN11A: Small Molecules and Peptides
Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage-gated, type XI, alpha subunit) mediates the voltage-dependent sodium ion permeability and conductance. It forms the pore of the sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform.
Cardiac Na+ channel blocker. Antiarrhythmic
| Chemical Name: | N-(2-Piperidylmethyl)-2,5-bis-(2,2,2-trifluoroethoxy)benzamide acetate |
| Purity: | ≥98% (HPLC) |
Inhibitor of neuronal NaV channels; anticonvulsant
| Alternate Names: | CBZ |
| Chemical Name: | 5H-Dibenz[b,f]azepine-5-carboxamide |
| Purity: | ≥98% (HPLC) |
NaV blocker; neuroprotective
| Alternate Names: | 619C89 |
| Chemical Name: | 2-(4-Methyl-1-piperazinyl)-5-(2,3,5-trichlorophenyl)-4-pyrimidinamine |
| Purity: | ≥98% (HPLC) |
Na+ channel blocker; antiarrhythmic agent
| Alternate Names: | Ko 1173 |
| Chemical Name: | 1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride |
| Purity: | ≥98% (HPLC) |
Antianginal, activates pyruvate dehydrogenase
| Alternate Names: | RS 43285 |
| Chemical Name: | N-(2,6-Dimethylphenyl)-4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]-1-piperazineacetamide dihydrochloride |
| Purity: | ≥98% (HPLC) |
Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)
| Alternate Names: | AD 810,CI 912 |
| Chemical Name: | 1,2-Benzisoxazole-3-methanesulfonamide |
| Purity: | ≥99% (HPLC) |
