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145 results for "ROCK2" in Products
ROCK2 Products
ROCK2/II (Rho-associated protein kinase 2; also Rho-kinase alpha) is a member of the AGC serine/threonine protein kinase family. ROCK2 is a downstream target of activated RhoA. Its activation results in myosin phosphorylation with subsequent muscle contraction. Human ROCK2 is 1388 amino acids (aa) in length, and appears to be present as a dimer. It contains a protein kinase domain (aa 92-354), a coiled-coil region (aa 429-1131) and a zinc-finger region (aa 1260-1315). Two isoforms show an alternate start site at M686, and a three aa substitution for the N-terminal 444 amino acids. Over aa 641-846, human ROCK2 shares 94% and 96% aa identity with mouse and canine ROCK2, respectively.
GMP Version Available:
TB1254-GMP
GMP
Alternate Names:
y27632,Y-27632 2HCl,ROCK inhibitor,ROCK1 inhibitor
Chemical Name:
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity:
≥98%
Chemical Name:
trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity:
≥99%
Reactivity:
Human, Mouse
Details:
Mouse IgG1 kappa Monoclonal Clone #1E12
Applications:
IHC, WB, ELISA, ICC/IF
![Western Blot: ROCK2 Antibody (1E12) [H00009475-M02]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-1E12-Western-Blot-H00009475-M02-img0009.jpg "Western Blot: ROCK2 Antibody (1E12) [H00009475-M02]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB
![Immunohistochemistry-Paraffin: ROCK2 Antibody [NBP1-86124]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-Immunohistochemistry-Paraffin-NBP1-86124-img0014.jpg "Immunohistochemistry-Paraffin: ROCK2 Antibody [NBP1-86124]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF, Mycoplasma
![Immunocytochemistry/ Immunofluorescence: ROCK2 Antibody [NBP2-20199]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-20199-img0005.jpg "Immunocytochemistry/ Immunofluorescence: ROCK2 Antibody [NBP2-20199]")
Chemical Name:
(3S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide dihydrochloride
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #GT11712
Applications:
IHC, WB
![Western Blot: ROCK2 Antibody (GT11712) [NBP3-13535]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-GT11712-Western-Blot-NBP3-13535-img0007.jpg "Western Blot: ROCK2 Antibody (GT11712) [NBP3-13535]")
Chemical Name:
(S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Goat IgG Polyclonal
Applications:
WB
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #23GB2030
Applications:
WB, Flow, ICC/IF, Mycoplasma
Reactivity:
Human
Assay Range:
0.312 - 20 ng/mL (example only; lot dependent)
Applications:
ELISA
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ELISA, ICC/IF
![Western Blot: ROCK2 AntibodyBSA Free [NBP1-76570]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-Western-Blot-NBP1-76570-img0001.jpg "Western Blot: ROCK2 AntibodyBSA Free [NBP1-76570]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #JE31-36
Applications:
IHC, WB, ICC/IF
Alternate Names:
HA 1077
Purity:
≥98%
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #HL1071
Applications:
WB, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #8G3U2
Applications:
IHC, WB, ELISA
![Western Blot: ROCK2 Antibody (8G3U2) [NBP3-16123]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-8G3U2-Western-Blot-NBP3-16123-img0002.jpg "Western Blot: ROCK2 Antibody (8G3U2) [NBP3-16123]")
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, IP
![Western Blot: ROCK2 Antibody [NB100-593]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-Western-Blot-NB100-593-img0006.jpg "Western Blot: ROCK2 Antibody [NB100-593]")
Chemical Name:
N-[3-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-6-yl]oxy]phenyl]-4-[2-(4-morpholinyl)ethoxy]benzamide
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #10E1
Applications:
WB, ELISA, ICC/IF
![Western Blot: ROCK2 Antibody (10E1) [NBP3-15152]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-10E1-Western-Blot-NBP3-15152-img0002.jpg "Western Blot: ROCK2 Antibody (10E1) [NBP3-15152]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Monoclonal Clone #S01-4F1
Applications:
WB, ICC/IF
![Western Blot: ROCK2 Antibody (S01-4F1) [NBP3-19508]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-S01-4F1-Western-Blot-NBP3-19508-img0002.jpg "Western Blot: ROCK2 Antibody (S01-4F1) [NBP3-19508]")
Reactivity:
Human
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
![Western Blot: ROCK2 Antibody [NBP2-58122]](https://resources.rndsystems.com/images/products/ROCK2-Antibody-Western-Blot-NBP2-58122-img0003.jpg "Western Blot: ROCK2 Antibody [NBP2-58122]")
Chemical Name:
(S)-(+)-4-Glycyl-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]-hexahydro-1H-1,4-diazepine dihydrochloride
Purity:
≥98%
Chemical Name:
(3S)-1-[[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yl]carbonyl]-3-pyrrolidinamine dihydrochloride
Purity:
≥98%
Alternate Names:
Azaindole-1,BAY-549
Chemical Name:
6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
Purity:
≥98%
Alternate Names:
Azaindole-1,BAY-549
Chemical Name:
6-Chloro-N4-[3,5-difluoro-4-[(3-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)oxy]phenyl]-2,4-pyrimidinediamine
Purity:
≥98%