14 results for "p38 alpha Small Molecules and Peptides" in Products
p38 alpha Small Molecules and Peptides
The p38 Mitogen-activated Protein Kinases (MAPKs) are a family of four related Ser/Thr kinases activated by proinflammatory cytokines and environmental stresses. All four p38 family members, alpha, beta, gamma, and delta, are phosphorylated by MKK3 and/or MKK6 at dual Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr. Once activated, p38 phosphorylates a number of targets, including the nuclear transcription factors ATF2 and Max.
The most frequently analyzed family ...
Selective inhibitor of p38 MAPK
Potent, selective inhibitor of p38 MAPK
Selective inhibitor of p38 MAPK; water-soluble
Potent p38 MAPK inhibitor; anti-inflammatory
Selective p38 MAPK inhibitor
High affinity and selective p38 kinase inhibitor
Potent and selective p38α inhibitor
Selective inhibitor of p38α and p38β2
Potent, selective p38α and p38β inhibitor
p38 MAPK inhibitor
p38 MAPK inhibitor; anti-inflammatory
Potent and selective p38α/β inhibitor
Potent and selective p38α and p38β Degrader (PROTAC®); active in vivo
Potent and selective p38α and p38β Degrader (PROTAC®); active in vivo