4 results for "Lysine (K)-specific Demethylase 4C/KDM4C Small Molecules and Peptides" in Products
Lysine (K)-specific Demethylase 4C/KDM4C: Small Molecules and Peptides
JMJD2C is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.
Histone KDM inhibitor; cell permeable
| Chemical Name: | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine ethyl ester |
| Purity: | ≥98% (HPLC) |
Pan Jumonji inhibitor; active in vivo
| Chemical Name: | 5-Chloro-2-[(E)-2-[phenyl(pyridin-2-yl)methylidene]hydrazin-1-yl]pyridine |
| Purity: | ≥98% (HPLC) |
Histone demethylase inhibitor; cell permeable
| Alternate Names: | 5-carboxy-8HQ |
| Chemical Name: | 8-Hydroxy-5-quinolinecarboxylic acid |
| Purity: | ≥98% (HPLC) |
Selective KDM2/7 inhibitor
| Chemical Name: | N-(9-Cyclopropyl-1-oxononyl)-N-hydroxy-β-alanine |
| Purity: | ≥98% (HPLC) |
