56 results for "LAG-3" in Products
LAG-3 Products
LAG-3 (Lymphocyte activation gene-3; CD223) is a transmembrane protein that binds to MHC class II molecules and negatively regulates T cell receptor signaling. It is expressed on activated T cells, NK cells, and plasmacytoid dendritic cells (pDC). LAG-3 limits the expansion of activated T cells and pDC in response to select stimuli. Proteolytic shedding of LAG-3 enables normal T cell activation by removing the negative regulation. Binding of a homodimerized soluble LAG-3/Ig fusion protein to MHC class II molecules induces maturation of immature DC as well as secretion of pro-inflammatory cytokines by cytotoxic CD8+ T cells and NK cells.
![Flow Cytometry: LAG-3 Antibody (11E3) - BSA Free [NBP1-97662]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-11E3-Flow-Cytometry-NBP1-97662-img0001.jpg "Flow Cytometry: LAG-3 Antibody (11E3) - BSA Free [NBP1-97662]")
![Western Blot: LAG-3 Antibody (BLR027F) [NBP2-76402]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-BLR027F-Western-Blot-NBP2-76402-img0007.jpg "Western Blot: LAG-3 Antibody (BLR027F) [NBP2-76402]")
![Western Blot: LAG-3 Antibody (BLR028F) [NBP2-76403]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-BLR028F-Western-Blot-NBP2-76403-img0003.jpg "Western Blot: LAG-3 Antibody (BLR028F) [NBP2-76403]")
![Flow Cytometry: LAG-3 Antibody Pack [NBP3-11743]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-Pack-Flow-Cytometry-NBP3-11743-img0001.jpg "Flow Cytometry: LAG-3 Antibody Pack [NBP3-11743]")
LAG-3 Antibody - IgG4SP, (Research Grade relatlimab Biosimilar) - Low Endotoxin, Azide and BSA Free
![Immunohistochemistry-Paraffin: LAG-3 Antibody [NBP1-85781]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-Immunohistochemistry-Paraffin-NBP1-85781-img0007.jpg "Immunohistochemistry-Paraffin: LAG-3 Antibody [NBP1-85781]")
Simple Plex cartridges are custom built to fit your needs. Choose from over 350 assays spanning human, mouse, rat, and non-human primate. Just select your sample type, cartridge size (16, 32, or 72 samples), and add up to 8 analytes per cartridge.
![Western Blot: LAG-3 Antibody (L4-PL33)Azide Free [NBP3-05777]](https://resources.rndsystems.com/images/products/LAG-3-Antibody-L4-PL33-Azide-Free-Western-Blot-NBP3-05777-img0001.jpg "Western Blot: LAG-3 Antibody (L4-PL33)Azide Free [NBP3-05777]")
