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9 results for "Histamine H3 R Small Molecules and Peptides" in Products

Histamine H3 R Small Molecules and Peptides

Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors Histamine H1 R, Histamine H2 R, Histamine H3 R and Histamine H4 R. HRH3 encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. Histamine H3 R is an integral membrane protein and can regulate neurotransmitter release. It can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

Alternate Names:
Org 3770,6-Azamianserin
Chemical Name:
1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine
Purity:
≥98%
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant

H3 antagonist; also H4 inverse agonist

Chemical Name:
N-Cyclohexyl-4-(imidazol-4-yl)-1-piperidinecarbothioamide
Purity:
≥98%
H3 antagonist; also H4 inverse agonist

Standard H3 and H4 agonist (H3 > H4)

Chemical Name:
5-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide
Purity:
≥98%
Standard H3 and H4 agonist (H3 > H4)

Highly potent H3 antagonist and H4 partial agonist

Alternate Names:
VUF 9153
Chemical Name:
N-(4-Chlorobenzyl)-S-[3-(4(5)-imidazolyl)propyl]isothiourea dihydrobromide
Purity:
≥98%
Highly potent H3 antagonist and H4 partial agonist

Standard H3 agonist. Also H4 agonist

Chemical Name:
4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide
Standard H3 agonist. Also H4 agonist

Endogenous histamine receptor agonist

Chemical Name:
2-(4-Imidazolyl)ethylamine dihydrochloride
Endogenous histamine receptor agonist

Selective 5-HT2A antagonist. Also antagonist at 5-HT1D

Alternate Names:
R 41 468
Chemical Name:
3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione (L)-tartrate
Purity:
≥97%
Selective 5-HT2A antagonist. Also antagonist at 5-HT1D

Highly potent H3 antagonist and H4 partial agonist

Alternate Names:
VUF 9153
Chemical Name:
N-(4-Chlorobenzyl)-S-[3-(4(5)-imidazolyl)propyl]isothiourea dihydrobromide
Purity:
≥98%
Highly potent H3 antagonist and H4 partial agonist

High affinity H3 antagonist

Chemical Name:
1-[3-[4-(1-Piperidinylmethyl)phenoxy]propyl]piperidine hydrochloride
Purity:
≥98%
High affinity H3 antagonist
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