Imetit dihydrobromide

Tocris Bioscience, part of Bio-Techne | Catalog # 0729

Standard H3 and H4 agonist (H3 > H4)
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Key Product Details

Description

Standard H3 and H4 agonist (H3 > H4)

View all Histamine H3 Receptor Agonists »

Product Description

Imetit dihydrobromide is an an extremely potent, high affinity agonist at H3 and H4 receptors (Ki values are 0.3 and 2.7 nM respectively). Induces shape change in eosinophils with an EC50 of 25 nM. Centrally active following systemic administration.

Product Specifications

Molecular Weight

332.06

Formula

C6H10N4S.2HBr

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

5-[2-(Imidazol-4-yl)ethyl]isothiourea dihydrobromide

CAS Number

32385-58-3

PubChem ID

11957573

InChI Key

DOBOYMKCRRLTRF-UHFFFAOYSA-N

SMILES

Br.Br.NC(=N)SCCC1=CNC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 33.21 100

Preparing Stock Solutions for Imetit dihydrobromide

The following data is based on the product molecular weight 332.06

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.01 mL 15.06 mL 30.12 mL
5 mM 0.60 mL 3.01 mL 6.02 mL
10 mM 0.30 mL 1.51 mL 3.01 mL
50 mM 0.06 mL 0.30 mL 0.60 mL

Calculators

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Background References

References are publications that support the biological activity of the product.

Product Documents for Imetit dihydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Imetit dihydrobromide

For research use only

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