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208 results for "GSK-3 beta" in Products
GSK-3 beta Products
GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.
GMP Version Available:
TB4423-GMP
GMP
Alternate Names:
CHIR99021,CT99021
Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥98%
Chemical Name:
6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity:
≥99%
Reactivity:
Human, Mouse, Rat, Primate
Details:
Mouse IgG2A Monoclonal Clone #3D10
Applications:
IHC, WB, ELISA, Flow, ICC/IF, + 1 More
![Western Blot: GSK-3 beta Antibody (3D10)BSA Free [NBP1-47470]](https://resources.rndsystems.com/images/products/GSK-3-beta-Antibody-3D10-Western-Blot-NBP1-47470-img0012.jpg "Western Blot: GSK-3 beta Antibody (3D10)BSA Free [NBP1-47470]")
Reactivity:
Human, Mouse, Rat, Mammal
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF
![GSK-3 beta [p Tyr279, p Tyr216] Antibody](https://resources.rndsystems.com/images/products/nb100-81946_rabbit-polyclonal-gsk-3-beta-p-tyr216-antibody-23420241523259.jpg "Immunohistochemistry-Paraffin: GSK-3 beta [p Tyr279, p Tyr216] Antibody [NB100-81946] -")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Rat IgG2B Monoclonal Clone #272536
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human, Mouse, Rat, Primate
Details:
Mouse IgG2A Monoclonal Clone #3D10
Applications:
IHC, WB, ELISA, Flow, ICC/IF, + 2 More
![Western Blot: GSK-3 beta Antibody (3D10)Azide and BSA Free [NBP2-80757]](https://resources.rndsystems.com/images/products/GSK-3-beta-Antibody-3D10-Azide-and-BSA-Free-Western-Blot-NBP2-80757-img0002.jpg "Western Blot: GSK-3 beta Antibody (3D10)Azide and BSA Free [NBP2-80757]")
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human, Mouse, Rat
Details:
Rabbit IgG Polyclonal
Applications:
IHC, WB, ICC/IF
![Western Blot: GSK-3 beta Antibody [NBP1-31353]](https://resources.rndsystems.com/images/products/GSK-3-beta-Antibody-Western-Blot-NBP1-31353-img0015.jpg "Western Blot: GSK-3 beta Antibody [NBP1-31353]")
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG2B Monoclonal Clone #GT1619
Applications:
IHC, WB, ICC/IF
![Western Blot: GSK-3 beta Antibody (GT1619) [NBP3-13691]](https://resources.rndsystems.com/images/products/GSK-3-beta-Antibody-GT1619-Western-Blot-NBP3-13691-img0008.jpg "Western Blot: GSK-3 beta Antibody (GT1619) [NBP3-13691]")
Chemical Name:
4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione
Purity:
≥97%
Chemical Name:
3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
Purity:
≥98%
Chemical Name:
3-[(3-Chloro-4-hydroxyphenyl)amino]-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione
Purity:
≥98%
Reactivity:
Human, Mouse
Details:
Mouse IgG2B Monoclonal Clone #833916
Applications:
WB, ICC/IF
Reactivity:
Human
Details:
Rat IgG2B Monoclonal Clone #272535
Applications:
ICC/IF
Reactivity:
Human
Details:
Mouse IgG1 Monoclonal Clone #609739
Applications:
WB, Flow, ICC/IF, CyTOF-ready
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #1253C
Applications:
WB, ICC/IF, Simple Western
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG2A Monoclonal Clone #GT16711
Applications:
IHC, WB, ICC/IF
![Western Blot: GSK-3 beta Antibody (GT16711) [NBP3-13679]](https://resources.rndsystems.com/images/products/GSK-3-beta-Antibody-GT16711-Western-Blot-NBP3-13679-img0005.jpg "Western Blot: GSK-3 beta Antibody (GT16711) [NBP3-13679]")
Reactivity:
Human
Source:
HEK293
Accession #:
P49841.2
Applications:
Enzyme Activity
Reactivity:
Human, Mouse
Details:
Mouse IgG1 Monoclonal Clone #3D6B4
Applications:
IHC, WB, ELISA, Flow, CyTOF-ready
![Western Blot: GSK-3 beta Antibody (3D6B4)BSA Free [NBP2-52478]](https://resources.rndsystems.com/images/products/GSK-3-beta-Antibody-3D6B4-Western-Blot-NBP2-52478-img0004.jpg "Western Blot: GSK-3 beta Antibody (3D6B4)BSA Free [NBP2-52478]")
Alternate Names:
6BIO
Chemical Name:
(2'Z,3'E)-6-Bromoindirubin-3'-oxime
Purity:
≥98%
Reactivity:
Human, Mouse, Rat
Assay Range:
156-10000 pg/mL
Applications:
ELISA
Reactivity:
Human
Details:
Rabbit IgG Monoclonal Clone #9G11
Applications:
IHC, WB, ELISA, ICC/IF
Reactivity:
Human, Mouse, Rat
Details:
Mouse IgG1 Monoclonal Clone #M131
Applications:
IHC, WB, ICC/IF
Reactivity:
Human
Source:
Sf 9 (baculovirus)
Accession #:
NM_001145156
Applications:
Bioactivity
