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63 results for "Fluorescent Probes Fluorescent Probes and Dyes" in Products

Fluorescent Probes: Fluorescent Probes and Dyes

Fluorescent probes bound to receptors or proteins enable researchers to detect particular components of complex biomolecular assemblies, such as live cells, with high sensitivity and selectivity. Tocris also offers a wide selection of fluorescent dyes and labels and stains.

Fluorescent lactic acid probe

Chemical Name: (2S)-2-Hydroxy-3-[(7-nitro-2,1,3-benzoselenadiazol-4-yl)amino]propanoic acid
Applications: Flow
Purity: ≥95% (HPLC)
Application of SCOTfluor lactic acid probe 510 in HeLa cells
(2)

Fluorescent glucose probe

Chemical Name: 2-Deoxy-2-[(7-nitro-2,1,3-benzoselenadiazol-4-yl)amino]-D-glucose
Purity: ≥98% (HPLC)
Application of SCOTfluor glucose probe 510 in HeLa cells
(3)

Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays

Purity: ≥95% (HPLC)
Fluorescent probe targeting kinases; kinase tracer for TR-FRET assays

Signal amplification kit for use in ISH, ICC and IHC

Applications: IHC, Dual ISH-IHC, ICC
Application of ClariTSA™ Fluorophore Kit 520 in RNAscope Multiplex Fluorescent v2 Assay

Fluorescent substrate for NET and VMAT2

Chemical Name: 3-(2-Aminoethyl)-8-fluoro-7-hydroxy-2H-chromen-2-one hydrochloride
Purity: ≥98% (HPLC)
FFN 270 application
(2)

Signal amplification kit for use in ISH, ICC and IHC

Applications: IHC, Dual ISH-IHC, ICC
Application of ClariTSA™ Fluorophore Kit 570 in RNAscope Multiplex Fluorescent v2 Assay

Signal amplification kit for use in ISH, ICC and IHC

Applications: IHC, Dual ISH-IHC, ICC
Application of ClariTSA™ Fluorophore Kit 650 in RNAscope Multiplex Fluorescent v2 Assay

Universal red fluorescent mitochondrial stain for both live and fixed cells

Purity: ≥95% (HPLC)
Applications: Flow, IHC, ICC
Mitobrilliant 646 product image
(3)

Red-orange fluorescent cytoskeleton stain. Binds and labels F-actin. Used for: F-actin staining. Application: fluorescent microscopy, immunofluorescence (IHC, ICC)

Chemical Name: 7-[(4R)-5-[[[[4-[3,6-Bis(dimethylamino)xanthylium-9-yl]-3-carboxyphenyl]amino]thioxomethyl]amino]-4-hydroxy-L-leucine]phalloidin
Purity: ≥90% (HPLC)
Applications in HeLa Cells for Phalloidin-TRITC
(2)

Fluorescent hydrogen peroxide indicator

Alternate Names: PO1
Chemical Name: 2',3',6',7'-Tetrahydro-12'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-spiro[isobenzofuran-1(3H),9'-[1H,5H,9H]xantheno[2,3,4-ij]quinolizin]-3-one
Purity: ≥98% (HPLC)
Fluorescent hydrogen peroxide indicator

High-affinity VHL fluorescent probe for TR-FRET and FP assays

Chemical Name: (2S,4R)-1-((S)-2-(tert-Butyl)-21-(5,5-difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-4,19-dioxo-6,9,12,15-tetraoxa-3,18-diazahenicosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Purity: ≥95% (HPLC)
High-affinity VHL fluorescent probe for TR-FRET and FP assays

Amyloid fibril-specific fluorescent probe. Used for: amyloid fibril detection. Application: fluorescence microscopy, confocal microscopy

Chemical Name: 4,4'-[(2-Bromo-1,4-phenylene)di-(1E)-2,1-ethenediyl]bisphenol
Purity: ≥98% (HPLC)
Amyloid fibril-specific fluorescent dye

H2S fluorescent probe

Chemical Name: N-[2-[(Acetyloxy)methoxy]-2-oxoethyl]-N-[(3',6'-diazido-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)carbonyl]glycine (acetyloxy)methyl ester
H2S fluorescent probe

Fluorescent BET bromodomain probe; suitable for use in TR-FRET

Chemical Name: (S)-5-(3-(1-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-2-oxo-7,10,13-trioxa-3-azahexadecan-16-yl)thioureido)-2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoic acid trifluoroacetate
Purity: ≥95% (HPLC)
Fluorescent BET bromodomain probe; suitable for use in TR-FRET

High affinity fluorescent probe for TR-FRET cereblon binding assay

Chemical Name: 3-(5,5-Difluoro-7,9-dimethyl-5H-5λ4,6λ4-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-3-yl)-N-(8-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamido)octyl)propenamide
Purity: ≥95% (HPLC)
High affinity fluorescent probe for TR-FRET cereblon binding assay

Amine-reactive fluorescent probe precursor

Chemical Name: 4-Fluoro-7-nitro-2,1,3-benzoselenadiazole
Purity: ≥90% (HPLC)
Amine-reactive fluorescent probe precursor

Green-fluorescent cytoskeleton stain. Binds and labels F-actin. Used for: F-actin staining. Application: fluorescent microscopy, immunofluorescence (IHC, ICC)

Chemical Name: 7-[(4R)-N5-[[(3',6'-Dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]thioxomethyl]-4-hydroxy-4-methyl-L-ornithine]phalloidin
Purity: ≥90% (HPLC)
Applications in HeLa Cells for Phalloidin-FITC
(2)

Cell permeable non-fluorescent compound; green-fluorescent in living cells once hydrolyzed. Used for: cell tracing and cell viability monitoring. Application: fluorescent microscopy and flow cytometry

Chemical Name: N,N'-[[3',6'-Bis(acetyloxy)-oxospiro[isobenzofuran-1-(3H),9'-(9H)xanthene]-4',5'-diyl]bis(methylene)]bis[N-[2-(acetyloxy)methoxy]-2-oxoethyl]glycine 1,1'-bis[(acetyloxy)methyl] ester
Applications: Flow
Purity: ≥90% (HPLC)
Cell permeable compound; hydrolyzed to become fluorescent in living cells

Fluorogenic srTAG probe for live cell imaging of FBKP12 (F36V/L) fusion proteins

Chemical Name: 4-((2-(2-(3-((R)-3-(3,4-Dimethoxyphenyl)-1-(((S)-1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carbonyl)oxy)propyl)phenoxy)acetamido)ethyl)carbamoyl)-2-(3-(3-fluoroazetidin-1-ium-1-ylidene)-7-(3-fluoroazetidin-1-yl)-5,5-dimethyl-3,5-dihydrodibenzo[b,e]silin-10-yl)benzoate
Purity: ≥95% (HPLC)
Fluorescent microscopy data of dTAG Janelia Fluor® 635 in HEK293 cells
(3)

Fluorescent dye. Used for: synaptic vesicles staining. Application: fluorescence microscopy

Alternate Names: FM4-64
Chemical Name: 4-[6-[4-(Diethylamino)phenyl]-1,3,5-hexatrien-1-yl]-1-[3-(triethylammonio)propyl]pyridinium dibromide
Purity: ≥95% (HPLC)
Fluorescent dye; stains synaptic vesicles

Terbium cryptate FRET donor for TR-FRET assay development; amine reactive for conjugation

CoraFluor 1, amine reactive product vial
(3)

GFP fluorophore mimic for imaging RNA in living cells; activated by binding Spinach2 and Broccoli aptamers

Chemical Name: (5Z)-5-[(3,5-Difluoro-4-hydroxyphenyl)methylene]-3,5-dihydro-2-methyl-3-(2,2,2-trifluoroethyl)-4H-imidazol-4-one
Purity: ≥98% (HPLC)
GFP fluorophore mimic for imaging RNA in living cells; activated by binding Spinach2 and Broccoli aptamers

Fluorescent mitochondrial hydrogen peroxide indicator. Used for: live cell imaging. Application: confocal microscopy

Chemical Name: [4-[4-[3-Oxo-6'-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3'-yl]-1-piperazinyl]butyl]triphenyl-phosphonium iodide
Fluorescent mitochondrial hydrogen peroxide indicator

Fluorescent glucose uptake indicator

Chemical Name: 2-Deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
Purity: ≥97% (HPLC)
Fluorescent glucose uptake indicator

Orange fluorescent mitochondrial stain for live cells, Δψm dependent

Purity: ≥95% (HPLC)
Applications: Flow
MitoBrilliant Live 549 product image
(2)
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