3 results for "EDNRA/Endothelin R Type A Small Molecules and Peptides" in Products
EDNRA/Endothelin R Type A: Small Molecules and Peptides
EDNRA and EDNRB (endothelin A and B receptors, respectively) are members of the rhodopsin-like 7-transmembrane receptor family. EDNRA binds endothelins ET-1 and ET-2 preferentially, and is expressed on vascular smooth muscle where it mediates vasoconstriction. EDNRB binds all three endothelin forms equally, and is expressed on endothelial cells where it mediates vasodilation.
| Alternate Names: | Ro 47-0203 |
| Chemical Name: | 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]benzenesulfonamide |
| Purity: | ≥98% (HPLC) |
| Chemical Name: | (αS)-α-[(4,6-Dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenylbenzenepropanoic acid |
| Purity: | ≥98% (HPLC) |
