CHRM2: Small Molecules and Peptides
Muscarinic receptors are G protein-coupled receptors that mediate the response to acetylcholine released from parasympathetic nerves. Their role in the unconscious regulation of organ and central nervous system function makes them potential therapeutic targets for a broad spectrum of diseases. CHRM2 is of particular interest because of its extensive pharmacological characterization with both orthosteric and allosteric ligands.
8 results for "CHRM2 Small Molecules and Peptides" in Products
8 results for "CHRM2 Small Molecules and Peptides" in Products
CHRM2: Small Molecules and Peptides
Muscarinic receptors are G protein-coupled receptors that mediate the response to acetylcholine released from parasympathetic nerves. Their role in the unconscious regulation of organ and central nervous system function makes them potential therapeutic targets for a broad spectrum of diseases. CHRM2 is of particular interest because of its extensive pharmacological characterization with both orthosteric and allosteric ligands.
Selective M2 antagonist
| Chemical Name: | N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate |
| Purity: | ≥98% (HPLC) |
Muscarinic agonist
| Chemical Name: | 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate |
| Purity: | ≥98% (HPLC) |
Selective M2 antagonist
| Alternate Names: | Otenzepad |
| Chemical Name: | 11-[[2-[(Diethylamino)methyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% (HPLC) |
Selective M1 muscarinic agonist
| Chemical Name: | 4-[[[(3-Chlorophenyl)amino]carbonyl]oxy]-N,N,N-trimethyl-2-butyn-1-aminium chloride |
| Purity: | ≥99% (HPLC) |
High affinity and selective M2 antagonist
| Chemical Name: | 11-[[4-[4-(Diethylamino)butyl]-1-piperidinyl]acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one |
| Purity: | ≥98% (HPLC) |
Positive allosteric modulator of M2 and M4 receptors
| Chemical Name: | 3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-thieno[2,3-b]pyridine-2-carboxamide |
| Purity: | ≥98% (HPLC) |
Potent M2/M4 antagonist
| Chemical Name: | N-[2-[2-[(Dipropylamino)methyl]-1-piperidinyl]ethyl]-5,6-dihydro-6-oxo-11H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide |
| Purity: | ≥98% (HPLC) |
Muscarinic agonist
| Chemical Name: | (3S-cis)-3-Ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]-2(3H)-furanone hydrochloride |
| Purity: | ≥98% (HPLC) |
