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17 results for "Additional Stem Cell Dedifferentiation Products" in Products

Additional Stem Cell Dedifferentiation Products Products

Highly selective GSK-3 inhibitor; acts as Wnt activator

Alternate Names: CHIR99021,CT99021
Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥98%
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)

CHIR 99021 synthesized to cGMP guidelines

Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥99%
CHIR 99021 synthesized to cGMP guidelines
(2)

Potent inhibitor of MEK1/2

Alternate Names: PD325901
Chemical Name: N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
Purity: ≥99% (HPLC)
Potent inhibitor of MEK1/2

Histone deacetylase inhibitor

Alternate Names: VPA,Sodium Valproate
Chemical Name: Sodium 2-propylpentanoate
Histone deacetylase inhibitor

Potent and selective inhibitor of TGF-βRI

Alternate Names: E-616452,SJN 2511,ALK5 Inhibitor II
Chemical Name: 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
Purity: ≥99% (HPLC)
Potent and selective inhibitor of TGF-βRI

Sterile-filtered 10 mM solution of CHIR 99021 pre-dissolved in DMSO

Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥97% (HPLC)
Sterile-filtered 10mM solution of CHIR 99021 pre-dissolved in water

RepSox synthesized to Ancillary Material Grade

Alternate Names: ALK5 Inhibitor II,SJN 2511,E-616452
Chemical Name: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Purity: ≥99%
RepSox synthesized to Ancillary Material Grade

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Chemical Name: 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide
p53 inhibitor. Also aryl hydrocarbon receptor agonist

Irreversible inhibitor of LSD1; also inhibits MAO

Alternate Names: 2-PCPA
Chemical Name: (±)-trans-2-Phenylcyclopropylamine hydrochloride
Purity: ≥98% (HPLC)
Irreversible inhibitor of LSD1; also inhibits MAO

Potent histone deacetylase inhibitor

Chemical Name: (2E,4E,6R)-7-(4-(Dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide
Purity: ≥95% (HPLC)
Potent histone deacetylase inhibitor

DNA methyltransferase inhibitor

Chemical Name: 4-Amino-1-β-D-ribofuranosyl-1,3,5-triazin-2(1H)-one
Purity: ≥98% (HPLC)
DNA methyltransferase inhibitor

Retinoic acid analog; RAR agonist

Alternate Names: Ro 13-7410
Chemical Name: 4-[(E)-2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl]benzoic acid
Purity: ≥98% (HPLC)
Retinoic acid analog; RAR agonist

GLP and G9a inhibitor

Chemical Name: 2-(Hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6,7-dimethoxy-N-[1-(phenylmethyl)-4-piperidinyl]-4-quinazolinamine trihydrochloride
Purity: ≥98% (HPLC)
GLP and G9a inhibitor

GSK-3β inhibitor; also inhibits cdks

Chemical Name: 9-Bromo-7,12-dihydro-indolo[3,2-d][1]benzazepin-6(5H)-one
Purity: ≥98% (HPLC)
GSK-3β inhibitor; also inhibits cdks

Oct3/4 inducer; induces expression of pluripotent-associated genes

Chemical Name: Ethyl 2-[(4-chlorophenyl)amino]-4-thiazolecarboxylate
Purity: ≥98% (HPLC)
Oct3/4 inducer; induces expression of pluripotent-associated genes

Highly potent and selective GSK-3 inhibitor

Chemical Name: N6-[2-[[4-(2,4-Dichlorophenyl)-5-(1H-imidazol-1-yl)-2-pyrimidinyl]amino]ethyl]-3-nitro-2,6-pyridinediamine
Purity: ≥98% (HPLC)
Highly potent and selective GSK-3 inhibitor

Non-nucleoside DNA methyltransferase inhibitor

Chemical Name: N-Phthalyl-L-tryptophan
Purity: ≥98% (HPLC)
Non-nucleoside DNA methyltransferase inhibitor
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