937 results for "ACE-2" in Products
ACE-2 Products
Angiotensin converting enzyme 2 (ACE-2), also known as ACEH (ACE homolog), is an integral membrane protein and a zinc metalloprotease of the ACE family. The predicted human ACE-2 protein sequence consists of 805 amino acids, including a N-terminal signal peptide, a single catalytic domain, a C-terminal membrane anchor, and a short cytoplasmic tail. ACE-2 cleaves angiotensins I and II as a carboxypeptidase.
ACE-2 also serves as the receptor for the SARS-CoV and SARS-CoV-2 viruses. Binding of the S1 domain of the SARS Coronavirus Spike protein to ACE-2 initiates viral entry into the host cell. Recently, this interaction between SARS-CoV-2 and ACE-2 has become an area of intense therapeutic interest to develop treatments against COVID-19.
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Kappa Monoclonal Clone #ACE2/8748R |
| Applications: | IHC, ELISA |
| Reactivity: | Human, Mouse, Rat, Hamster |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, Flow, IHC, IP, +1 More |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #535919 |
| Applications: | Flow |
| Alternate Names: | FG 4592 |
| Chemical Name: | N-[(4-Hydroxy-1-methyl-7-phenoxy-3-isoquinolinyl)carbonyl]glycine |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Hamster |
| Details: | Mouse IgG2a Monoclonal Clone #171606 |
| Applications: | WB, IHC |
| Chemical Name: | N-[(1S)-1-Carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-L-histidine |
| Purity: | ≥98% (HPLC) |