9 results for "5-HT6 Small Molecules and Peptides" in Products
5-HT6: Small Molecules and Peptides
5-HT6 is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. It belongs to the G protein-coupled receptor 1 family. 5-HT6 is expressed in several human brain regions, most prominently in the caudate nucleus. The activity of 5-HT6 is mediated by G proteins that stimulate adenylate cyclase. 5-HT6 has a high affinity for tricyclic psychotropic drugs.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective 5-HT6 antagonist
| Chemical Name: | N-(1-(5-Chloro-2,3-dimethoxyphenyl)ethyl)-2-(methylsulfonyl)-5-(piperazin-1-yl)aniline hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT6 agonist
| Chemical Name: | 5-Chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole hydrochloride |
| Purity: | ≥99% (HPLC) |
Selective 5-HT6 antagonist; orally active
| Chemical Name: | 5-Chloro-N-[4-methoxy-3-(1-piperazinyl)phenyl]-3-methyl-benzo[b]thiophen-2-sulfonamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent and selective 5-HT6 antagonist
| Chemical Name: | N-(3,5-Dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)benzenesulfonamide hydrochloride |
| Purity: | ≥98% (HPLC) |
High affinity 5-HT6 antagonist
| Chemical Name: | 5-Methoxy-N,N-dimethyl-2-phenyl-1H-indole-3-ethanamine |
| Purity: | ≥98% (HPLC) |
Selective 5-HT6 agonist
| Chemical Name: | 3-[(-3-Fluorophenyl)sulfonyl]-N,N-dimethyl-1H-pyrrolo[2,3-b]pyridine-1-ethanamine dihydrochloride |
| Purity: | ≥99% (HPLC) |
High affinity and selective 5-HT6 agonist
| Chemical Name: | 1-[(6-Chloroimidazo[2,1-b]thiazol-5-yl)sulfonyl]-1H-indole-3-ethanamine oxalate |
| Purity: | ≥98% (HPLC) |
Potent, selective 5-HT6 antagonist
| Chemical Name: | 4-Iodo-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]benzenesulfonamide hydrochloride |
| Purity: | ≥98% (HPLC) |
