6 results for "5-HT3 Receptor Antagonists Small Molecules and Peptides" in Products
5-HT3 Receptor Antagonists: Small Molecules and Peptides
Serotonin 5-HT3 receptors, are ligand-gated ion channels of the Cys-loop family. The receptor consists of 4-transmembrane domains that form an intrinsic cation-selective channel. So far five human 5-HT3 receptor subtypes have been identified (5-HT3A-E).
The 5-HT3B-E subtypes do not form functional homo-oligomeric complexes like the 5-HT3A subtypes, but co-assemble with 5-HT3A to influence its functional expression.
Selective 5-HT3 antagonist
| Alternate Names: | GR 38032 |
| Chemical Name: | 1,2,3,9-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-4H-carbazol-4-one hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT2 antagonist; also 5-HT3, H1 and α2 antagonist; antidepressant
| Alternate Names: | Org 3770,6-Azamianserin |
| Chemical Name: | 1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benzazepine |
| Purity: | ≥98% (HPLC) |
5-HT3 antagonist
| Chemical Name: | Tropanyl 3,5-dichlorobenzoate |
| Purity: | ≥98% (HPLC) |
5-HT3 antagonist
| Alternate Names: | BRL 43694 |
| Chemical Name: | 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Highly potent 5-HT3 antagonist; also 5-HT4 agonist
| Chemical Name: | (±)-4-Amino-N-1-azabicyclo[2.2.2]oct-3-yl-5-chloro-2-methoxybenzamide hydrochloride |
| Purity: | ≥98% (HPLC) |
Potent 5-HT3 antagonist; also α7 nAChR partial agonist
| Alternate Names: | Novaban,ICS 205930 |
| Chemical Name: | (3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylic acid ester monohydrochloride |
| Purity: | ≥98% (HPLC) |
