17 results for "VEGFR2/KDR/Flk-1 Small Molecules and Peptides" in Products
VEGFR2/KDR/Flk-1 Small Molecules and Peptides
VEGFR2/KDR/Flk-1 (vascular endothelial growth factor receptor 2) is a transmembrane receptor tyrosine kinase that mediates the angiogenic effects of VEGF-A and VEGF-C. It is expressed primarily on vascular endothelial cells and endothelial cell progenitors. It is also expressed on endometrial epithelium, hematopoietic stem cells, liver sinusoidal endothelial cells, Sertoli cells and Leydig cells, platelets and megakaryocytes, sensory and autonomic neurons, Schwann cells, Muller glial cells, retinal progenitors, and osteoblasts. VEGFR2 can associate with VEGFR1, and a soluble form of VEGFR2 can circulate in the serum.
Src tyrosine kinase inhibitor
c-Fms inhibitor; suppresses osteolysis and osteoclast accumulation
VEGFR inhibitor. Also inhibits KIT, RET, MET and FLT3
Potent, selective inhibitor of VEGFR-2
Potent, selective VEGFR-2 inhibitor
Potent VEGFR, PDGFR and FGFR inhibitor
Dual site Src kinase inhibitor
Potent VEGFR-1, -2 and -3 inhibitor
Potent Raf-1 inhibitor; also inhibits VEGFR-2, VEGFR-3, PDGFR-β, Flt-3 and cKIT
Potent VEGFR, PDGFRβ and KIT inhibitor
Potent EGFR and VEGFR inhibitor
Potent VEGFR inhibitor; also inhibits other RTKs
Potent VEGFR inhibitor; also aromatase inhibitor
Potent inhibitor of VEGFR, PDGFR and FGFR
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
Potent inhibitor of PDGFRβ, KDR, FLT3 and CSF-1R
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity